Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/14188
Title
The Association of Nighttime Fasting Duration and Prostate Cancer Risk: Results from the Multicase-Control (MCC) Study in Spain
Author(s)
Palomar-Cros, Anna | Espinosa, Ana | Straif, Kurt | Perez-Gomez, Beatriz ISCIII | Papantoniou, Kyriaki | Gómez-Acebo, Inés | Molina-Barceló, Ana | Olmedo-Requena, Rocío | Alguacil, Juan | Fernández-Tardón, Guillermo | Casabonne, Delphine | Aragones, Nuria ISCIII | Castaño-Vinyals, Gemma | Pollan-Santamaria, Marina ISCIII | Romaguera, Dora | Kogevinas, Manolis
Date issued
2021-07-30
Citation
Nutrients. 2021;13(8):2662.
Language
Inglés
Document type
journal article
Abstract
Nighttime fasting has been inconclusively associated with a reduced risk of cancer. The purpose of this study was to investigate this association in relation to prostate cancer risk. We examined data from 607 prostate cancer cases and 848 population controls who had never worked in night shift work from the Spanish multicase-control (MCC) study, 2008-2013. Through an interview, we collected circadian information on meal timing at mid-age. We estimated odds ratios (OR) and 95% confidence intervals (CI) with unconditional logistic regression. After controlling for time of breakfast, fasting for more than 11 h overnight (the median duration among controls) was associated with a reduced risk of prostate cancer compared to those fasting for 11 h or less (OR = 0.77, 95% 0.54-1.07). Combining a long nighttime fasting and an early breakfast was associated with a lower risk of prostate cancer compared to a short nighttime fasting and a late breakfast (OR = 0.54, 95% CI 0.27-1.04). This study suggests that a prolonged nighttime fasting duration and an early breakfast may be associated with a lower risk of prostate cancer. Findings should be interpreted cautiously and add to growing evidence on the importance of chrononutrition in relation to cancer risk.
Subject
Breakfast | Chrononutrition | Circadian rhythms | Early time-restricted feeding | Prolonged nighttime fasting | Prostate cancer
Online version
DOI
Collections
- Investigación > IIS > IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
- Investigación > IIS > IDIVAL - Instituto de Investigación Marqués de Valdecilla (Cantabria)
- Investigación > IIS > ISPA - Instituto de Investigación Sanitaria del Principado de Asturias (Asturias)
- Investigación > IIS > IMIM - Hospital del Mar Research Institute-Barcelona (Cataluña)
- Investigación > ISCIII > Centro Nacional de Epidemiología (CNE)
- Investigación > IIS > ibs.GRANADA - Instituto de Investigación Biosanitaria de Granada (Andalucía)
- Investigación > IIS > IDIBELL - Instituto de Investigación Biomédica de Bellvitge (Cataluña)