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La Comisión Interministerial de Biomonitorización Humana en España: un reto hecho realidad
La Comisión Interministerial de Biomonitorización Humana (CIBMH) emana del Plan Estratégico de Salud y Medio Ambiente (PESMA), como una herramienta para la implementación de la biomonitorización humana (BMH) a nivel nacional, asegurando su integración con las estrategias europeas. La BMH tiene como...
Characterisation of Legionella Clinical Isolates in Spain from 2012 to 2022
Although cases of Legionnaires’ disease are notifiable, data on the phenotypic and genotypic characterisation of clinical isolates are limited. This retrospective study aims to report the results of the characterisation of Legionella clinical isolates in Spain from 2012 to 2022. Monoclonal antibodi...
El Proyecto H2020 URBANOME: Calidad del Aire, Salud y Participación Ciudadana
La intervención “Rutas Escolares Saludables” es el resultado de los procesos de co-creación y prototipado llevados a cabo en el Laboratorio ciudadano URBANMADLAB, creado en el marco del proyecto europeo H2020 URBANOME. El objetivo principal de la intervención es el de promover una mejora de la cali...
Fulminant septic shock due to community-acquired pneumonia caused by Legionella pneumophila SG1 Olda OLDA ST1. Case report
Legionellers' desease accounts for 1-8 % of cases of severe community-acquired pneumonia (CAP). Legionella spp. Is the causative organism that can result in respiratory failure, multi-organ dysfunction, sepsis, and death. Therefore, rapid diagnosis and efficient treatment are crucial. We report the...
Immune response against the SARS-CoV-2 spike protein in cancer patients after COVID-19 vaccination during the Omicron wave: a prospective study
Background: Cancer patients often have weakened immune systems, resulting in a lower response to vaccines, especially those receiving immunosuppressive oncological treatment (OT). We aimed to assess the impact of OT on the humoral and T-cell response to the B.1 lineage and Omicron variant following...
Assessing the functional relevance of splice isoforms.
Alternative splicing of messenger RNA can generate an array of mature transcripts, but it is not clear how many go on to produce functionally relevant protein isoforms. There is only limited evidence for alternative proteins in proteomics analyses and data from population genetic variation studies ...
Malondialdehyde-modified HDL particles elicit a specific IgG response in abdominal aortic aneurysm.
High Density Lipoprotein (HDL) plays a protective role in abdominal aortic aneurysm (AAA); however, recent findings suggest that oxidative modifications could lead to dysfunctional HDL in AAA. This study aimed at testing the effect of oxidized HDL on aortic lesions and humoral immune responses in a...
COVID-19-associated pulmonary aspergillosis (CAPA) in hematological patients: Could antifungal prophylaxis be necessary? A nationwide study
Background: COVID-19-associated pulmonary aspergillosis (CAPA) has emerged as a relatively common complication. Multiple studies described this relationship in critical patients, however its incidence and outcome in other risk groups such as immunosuppressed patients remains unknown. In this sense,...