REPISALUD is the institutional repository of the Instituto de Salud Carlos III (ISCIII) and its foundations: the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro Nacional de Investigaciones Oncológicas (CNIO). This repository gathers both scientific and academic production of these institutions in a single, open-access digital archive.
Communities in REPISALUD
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1
Glioblastoma multiforme (GBM) is an aggressive form of brain cancer with poor prognosis. Cancer cells are characterized by a specific redox environment that adjusts metabolism to its specific needs and allows the tumor to grow and metastasize. As a consequence, cancer cells and esp...
Do sex and site matter? Different age distribution in melanoma of the trunk among Swedish men and women
BACKGROUND: Recent research on cutaneous malignant melanoma (CMM) points to the coexistence of several biological pathways linked to the anatomical site of the lesion, which could lead to this neoplasm. Although the different anatomical distribution of CMM by sex is usually attributed t...
Limiting Cumulative HIV Viremia Copy-Years by Early Treatment Reduces Risk of AIDS and Death
BACKGROUND: Viremia copy-years (VCY), a time-updated measure of cumulative HIV exposure, predicts AIDS/death; although its utility in deciding when to start combination antiretroviral therapy (cART) remains unclear. We aimed to assess the impact of initiating versus deferring cART on risk of...