REPISALUD es el REPositorio Institucional de SALUD del Instituto de Salud Carlos III (ISCIII) y sus Fundaciones, el
Centro Nacional de Investigaciones Cardiovasculares (CNIC) y el Centro Nacional de Investigaciones Oncológicas (CNIO),
en el que se recoge en un único archivo digital y de acceso libre, la producción científica y académica de estos centros
de referencia en sus áreas.
Informes y estudios institucionales del ISCIII sobre COVID-19
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Colchicine in acute heart failure: Rationale and design of a randomized double-blind placebo-controlled trial (COLICA).
AIMS
Heart failure (HF) elicits a pro-inflammatory state, which is associated with impaired clinical outcomes, but no anti-inflammatory therapies have demonstrated a clinical benefit yet. Inflammatory pathways related with the interleukin-1 axis are overactivated during episodes of acute HF. Colch...
RhoA/rho kinase pathway activation in age-associated endothelial cell dysfunction and thrombosis.
The small GTPase RhoA and the downstream Rho kinase (ROCK) regulate several cell functions and pathological processes in the vascular system that contribute to the age-dependent risk of cardiovascular disease, including endothelial dysfunction, excessive permeability, inflammation, impaired angioge...
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