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dc.contributor.authorPalomar-Cros, Anna
dc.contributor.authorEspinosa, Ana
dc.contributor.authorStraif, Kurt
dc.contributor.authorPerez-Gomez, Beatriz 
dc.contributor.authorPapantoniou, Kyriaki
dc.contributor.authorGómez-Acebo, Inés
dc.contributor.authorMolina-Barceló, Ana
dc.contributor.authorOlmedo-Requena, Rocío
dc.contributor.authorAlguacil, Juan
dc.contributor.authorFernández-Tardón, Guillermo
dc.contributor.authorCasabonne, Delphine
dc.contributor.authorAragones, Nuria 
dc.contributor.authorCastaño-Vinyals, Gemma
dc.contributor.authorPollan-Santamaria, Marina 
dc.contributor.authorRomaguera, Dora
dc.contributor.authorKogevinas, Manolis
dc.identifier.citationNutrients. 2021;13(8):2662.es_ES
dc.description.abstractNighttime fasting has been inconclusively associated with a reduced risk of cancer. The purpose of this study was to investigate this association in relation to prostate cancer risk. We examined data from 607 prostate cancer cases and 848 population controls who had never worked in night shift work from the Spanish multicase-control (MCC) study, 2008-2013. Through an interview, we collected circadian information on meal timing at mid-age. We estimated odds ratios (OR) and 95% confidence intervals (CI) with unconditional logistic regression. After controlling for time of breakfast, fasting for more than 11 h overnight (the median duration among controls) was associated with a reduced risk of prostate cancer compared to those fasting for 11 h or less (OR = 0.77, 95% 0.54-1.07). Combining a long nighttime fasting and an early breakfast was associated with a lower risk of prostate cancer compared to a short nighttime fasting and a late breakfast (OR = 0.54, 95% CI 0.27-1.04). This study suggests that a prolonged nighttime fasting duration and an early breakfast may be associated with a lower risk of prostate cancer. Findings should be interpreted cautiously and add to growing evidence on the importance of chrononutrition in relation to cancer risk.es_ES
dc.description.sponsorshipInstituto de Salud Carlos III FIS PI11/01889. Anna Palomar-Cros is supported by a MINECO (Ministry of Economy in Spain) fellowship. We acknowledge support from the Spanish State Research Agency and Ministry of Science and Innovation through the “Centro de Excelencia Severo Ochoa 2019–2023” Program (CEX2018-000806-S), and support from the Generalitat de Catalunya through the CERCA Program.es_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.subjectCircadian rhythmses_ES
dc.subjectEarly time-restricted feedinges_ES
dc.subjectProlonged nighttime fastinges_ES
dc.subjectProstate canceres_ES
dc.titleThe Association of Nighttime Fasting Duration and Prostate Cancer Risk: Results from the Multicase-Control (MCC) Study in Spaines_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III es_ES
dc.contributor.funderMinisterio de Economía (España) es_ES
dc.contributor.funderMinisterio de Ciencia e Innovación (España) es_ES
dc.contributor.funderGovernment of Catalonia (España) es_ES
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España) es_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.rights.accessRightsopen accesses_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/FIS PI11/01889es_ES

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