dc.contributor.author | Solans, Marta | |
dc.contributor.author | Castelló Pastor, Adela | |
dc.contributor.author | Benavente, Yolanda | |
dc.contributor.author | Marcos-Gragera, Rafael | |
dc.contributor.author | Amiano, Pilar | |
dc.contributor.author | Gràcia-Lavedan, Esther | |
dc.contributor.author | Costas, Laura | |
dc.contributor.author | Robles, Claudia | |
dc.contributor.author | Gonzalez-Barca, Eva | |
dc.contributor.author | de la Banda, Esmeralda | |
dc.contributor.author | Alonso, Esther | |
dc.contributor.author | Aymerich, Marta | |
dc.contributor.author | Campo, Elias | |
dc.contributor.author | Dierssen-Sotos, Trinidad | |
dc.contributor.author | Fernández-Tardón, Guillermo | |
dc.contributor.author | Olmedo-Requena, Rocio | |
dc.contributor.author | Gimeno, Eva | |
dc.contributor.author | Castaño-Vinyals, Gemma | |
dc.contributor.author | Aragones, Nuria | |
dc.contributor.author | Kogevinas, Manolis | |
dc.contributor.author | de Sanjose, Silvia | |
dc.contributor.author | Pollan-Santamaria, Marina | |
dc.contributor.author | Casabonne, Delphine | |
dc.date.accessioned | 2019-11-04T10:11:41Z | |
dc.date.available | 2019-11-04T10:11:41Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Haematologica. 2018 Nov;103(11):1881-1888. | es_ES |
dc.identifier.issn | 0390-6078 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/8550 | |
dc.description.abstract | Diet is a modifiable risk factor for several neoplasms but evidence for chronic lymphocytic leukemia (CLL) is sparse. Previous studies examining the association between single-food items and CLL risk have yielded mixed results, while few studies have been conducted on overall diet, reporting inconclusive findings. This study aimed to evaluate the association between adherence to three dietary patterns and CLL in the multicase-control study (MCC-Spain) study. Anthropometric, sociodemographic, medical and dietary information was collected for 369 CLL cases and 1605 controls. Three validated dietary patterns, Western, Prudent and Mediterranean, were reconstructed in the MCC-Spain data. The association between adherence to each dietary pattern and CLL was assessed, overall and by Rai stage, using mixed logistic regression models adjusted for potential confounders. High adherence to a Western dietary pattern (i.e. high intake of high-fat dairy products, processed meat, refined grains, sweets, caloric drinks, and convenience food) was associated with CLL [ORQ4 vs. Q1=1.63 (95%CI 1.11; 2.39); P-trend=0.02; OR 1-SD increase=1.19 (95%CI: 1.03; 1.37)], independently of Rai stages. No differences in the association were observed according to sex, Body Mass Index, energy intake, tobacco, physical activity, working on a farm, or family history of hematologic malignancies. No associations were observed for Mediterranean and Prudent dietary patterns and CLL. This study provides the first evidence for an association between a Western dietary pattern and CLL, suggesting that a proportion of CLL cases could be prevented by modifying dietary habits. Further research, especially with a prospective design, is warranted to confirm these findings. | es_ES |
dc.description.sponsorship | Predoctoral contract to MS (CIBERESP), Spanish Ministry of Economy and Competitiveness Juan de la Cierva de Incorporación grant IJCI-2014-20900. Spanish Ministry of Economy and Competitiveness - Carlos III Institute of Health cofunded by FEDER funds/European Regional Develpment Fund (ERDF) - a way to build Europe [(grants PI17/01280, PI11/01810, PI14/01219, PI11/02213, PI09/1662, PI15/00966, RCESP C03/09, RTICESP C03/10, RTIC RD06/0020/0095, RD12/0036/0056, Rio Hortega CM13/00232, SV-09-CLINIC-1 and Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERE-SP))] and the Agència de Gestió d’Ajuts Universitaris i de Recerca AGAUR (2017SGR1085, 2014SGR756). The ICGC CLL-Genome Project was funded by Spanish Ministerio de Economía y Competitividad (MINECO) through the Instituto de Salud Carlos III (ISCIII), PMP15/00007 and Centro de Investigación Biomédica en Red: Oncología (CIBERONC). ISGlobal is a member of the CERCA Programme, Generalitat de Catalunya. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Fondazione Ferrata Storti | es_ES |
dc.type.hasVersion | SMUR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject.mesh | Adult | es_ES |
dc.subject.mesh | Aged | es_ES |
dc.subject.mesh | Aged, 80 and over | es_ES |
dc.subject.mesh | Body Mass Index | es_ES |
dc.subject.mesh | Case-Control Studies | es_ES |
dc.subject.mesh | Diet, Mediterranean | es_ES |
dc.subject.mesh | Diet, Western | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Leukemia, Lymphocytic, Chronic, B-Cell | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Middle Aged | es_ES |
dc.subject.mesh | Sex Factors | es_ES |
dc.subject.mesh | Spain | es_ES |
dc.subject.mesh | Energy Intake | es_ES |
dc.title | Adherence to the Western, Prudent, and Mediterranean dietary patterns and chronic lymphocytic leukemia in the MCC-Spain study | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución-NoComercial 4.0 Internacional | * |
dc.identifier.pubmedID | 29954942 | es_ES |
dc.format.volume | 103 | es_ES |
dc.format.number | 11 | es_ES |
dc.format.page | 1881-1888 | es_ES |
dc.identifier.doi | 10.3324/haematol.2018.192526 | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.contributor.funder | Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) | |
dc.contributor.funder | Centro de Investigación Biomedica en Red - CIBER | |
dc.contributor.funder | Government of Catalonia (España) | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1592-8721 | es_ES |
dc.relation.publisherversion | https://doi.org/10.3324/haematol.2018.192526 | es_ES |
dc.identifier.journal | Haematologica | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Epidemiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/IJCI-2014-20900 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI17/01280 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI11/01810 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI14/01219 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI11/02213 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI09/1662 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI15/00966 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RCESP C03/09 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RTICESP C03/10 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RTIC RD06/0020/0095 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RD12/0036/0056 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/CM13/00232 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/2017SGR1085 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/2014SGR756 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PMP15/00007 | es_ES |
dc.rights.accessRights | open access | es_ES |