Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/17432
Título
A 14-year Prospective Study of Human Coronavirus Infections in Hospitalized Children: Comparison With Other Respiratory Viruses
Autor(es)
Fecha de publicación
2020-08
Cita
Pediatr Infect Dis J. 2020 Aug;39(8):653-657.
Idioma
Inglés
Tipo de documento
research article
Resumen
Background: Human coronaviruses (HCoVs) have been recognized as causative agents of respiratory tract infections.Our aim was to describe HCoV infections in hospitalized children in a prospective surveillance study for 14 years and compare them with other respiratory viruses. Methods: As a part of an ongoing prospective study to identify the etiology of viral respiratory infections in Spain, we performed the analysis of HCoV infections in children hospitalized in a secondary hospital in Madrid, between October 2005 and June 2018. Clinical data of HCoV patients were compared with those infected by rhinovirus, respiratory syncytial virus and influenza. Results: The study population consisted of 5131 hospitalizations for respiratory causes in children. A total of 3901 cases (75.9%) had a positive viral identification and 205 cases (4.1%) were positive for HCoV. Only 41 cases (20%) of HCoV infection were detected as single infections. Episodes of recurrent wheezing were the most common diagnosis, and 112 children (54%) had hypoxia. Clinical data in HCoV cases were similar to those associated with rhinovirus; however, patients with HCoV were younger. Other viruses were associated with hypoxia more frequently than cases with HCoV; high fever was more common in influenza infections and bronchiolitis in respiratory syncytial virus group. Although a slight peak of circulation appears mostly in winter, HCoV has been detected throughout the year as well. Conclusions: HCoV infections represent a small fraction of respiratory infections that require hospitalization in children and their characteristics do not differ greatly from other respiratory viral infections.
MESH
Hospitalization | Adolescent | Age Distribution | Betacoronavirus | Bronchiolitis, Viral | COVID-19 | Child | Child, Preschool | Coronavirus Infections | Coronavirus NL63, Human | Coronavirus OC43, Human | Female | Fever | Humans | Hypoxia | Infant | Infant, Newborn | Influenza, Human | Male | Middle East Respiratory Syndrome Coronavirus | Pandemics | Picornaviridae Infections | Pneumonia, Viral | Prospective Studies | Respiratory Sounds | Respiratory Syncytial Virus Infections | Respiratory Tract Infections | Rhinovirus | Severe acute respiratory syndrome-related coronavirus | SARS-CoV-2 | Seasons | Severe Acute Respiratory Syndrome | Severity of Illness Index | Spain
Versión en línea
DOI
Aparece en las colecciones