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dc.contributor.author | Calvo, Cristina | |
dc.contributor.author | Alcolea, Sonia | |
dc.contributor.author | Casas, Inmaculada | |
dc.contributor.author | Pozo, Francisco | |
dc.contributor.author | Iglesias, María | |
dc.contributor.author | Gonzalez-Esguevillas, Mónica | |
dc.contributor.author | Luz García-García, María | |
dc.date.accessioned | 2024-02-02T11:22:30Z | |
dc.date.available | 2024-02-02T11:22:30Z | |
dc.date.issued | 2020-08 | |
dc.identifier.citation | Pediatr Infect Dis J. 2020 Aug;39(8):653-657. | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/17432 | |
dc.description.abstract | Background: Human coronaviruses (HCoVs) have been recognized as causative agents of respiratory tract infections.Our aim was to describe HCoV infections in hospitalized children in a prospective surveillance study for 14 years and compare them with other respiratory viruses. Methods: As a part of an ongoing prospective study to identify the etiology of viral respiratory infections in Spain, we performed the analysis of HCoV infections in children hospitalized in a secondary hospital in Madrid, between October 2005 and June 2018. Clinical data of HCoV patients were compared with those infected by rhinovirus, respiratory syncytial virus and influenza. Results: The study population consisted of 5131 hospitalizations for respiratory causes in children. A total of 3901 cases (75.9%) had a positive viral identification and 205 cases (4.1%) were positive for HCoV. Only 41 cases (20%) of HCoV infection were detected as single infections. Episodes of recurrent wheezing were the most common diagnosis, and 112 children (54%) had hypoxia. Clinical data in HCoV cases were similar to those associated with rhinovirus; however, patients with HCoV were younger. Other viruses were associated with hypoxia more frequently than cases with HCoV; high fever was more common in influenza infections and bronchiolitis in respiratory syncytial virus group. Although a slight peak of circulation appears mostly in winter, HCoV has been detected throughout the year as well. Conclusions: HCoV infections represent a small fraction of respiratory infections that require hospitalization in children and their characteristics do not differ greatly from other respiratory viral infections. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Lippincott Williams & Wilkins (LWW) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject.mesh | Hospitalization | es_ES |
dc.subject.mesh | Adolescent | es_ES |
dc.subject.mesh | Age Distribution | es_ES |
dc.subject.mesh | Betacoronavirus | es_ES |
dc.subject.mesh | Bronchiolitis, Viral | es_ES |
dc.subject.mesh | COVID-19 | es_ES |
dc.subject.mesh | Child | es_ES |
dc.subject.mesh | Child, Preschool | es_ES |
dc.subject.mesh | Coronavirus Infections | es_ES |
dc.subject.mesh | Coronavirus NL63, Human | es_ES |
dc.subject.mesh | Coronavirus OC43, Human | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Fever | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Hypoxia | es_ES |
dc.subject.mesh | Infant | es_ES |
dc.subject.mesh | Infant, Newborn | es_ES |
dc.subject.mesh | Influenza, Human | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Middle East Respiratory Syndrome Coronavirus | es_ES |
dc.subject.mesh | Pandemics | es_ES |
dc.subject.mesh | Picornaviridae Infections | es_ES |
dc.subject.mesh | Pneumonia, Viral | es_ES |
dc.subject.mesh | Prospective Studies | es_ES |
dc.subject.mesh | Respiratory Sounds | es_ES |
dc.subject.mesh | Respiratory Syncytial Virus Infections | es_ES |
dc.subject.mesh | Respiratory Tract Infections | es_ES |
dc.subject.mesh | Rhinovirus | es_ES |
dc.subject.mesh | Severe acute respiratory syndrome-related coronavirus | es_ES |
dc.subject.mesh | SARS-CoV-2 | es_ES |
dc.subject.mesh | Seasons | es_ES |
dc.subject.mesh | Severe Acute Respiratory Syndrome | es_ES |
dc.subject.mesh | Severity of Illness Index | es_ES |
dc.subject.mesh | Spain | es_ES |
dc.title | A 14-year Prospective Study of Human Coronavirus Infections in Hospitalized Children: Comparison With Other Respiratory Viruses | es_ES |
dc.type | research article | es_ES |
dc.rights.license | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.identifier.pubmedID | 32453196 | es_ES |
dc.format.volume | 39 | es_ES |
dc.format.number | 8 | es_ES |
dc.format.page | 653-657 | es_ES |
dc.identifier.doi | 10.1097/INF.0000000000002760 | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1532-0987 | es_ES |
dc.relation.publisherversion | https://doi.org/10.1097/INF.0000000000002760 | es_ES |
dc.identifier.journal | The Pediatric infectious disease journal | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Microbiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.rights.accessRights | open access | es_ES |
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