Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/20317
Título
SEOM clinical guidelines for the management of germ cell testicular cancer (2016)
Autor(es)
Fecha de publicación
2016-12
Cita
Aparicio J., Terrasa Pons Josefa, Duran I., Germa-Lluch J. R., Girones R., Gonzalez-Billalabeitia E., et al. SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clin Transl Oncol. 2016 Dec;18(12):1187-1196. Epub 2016 Nov 4.
Idioma
Inglés
Tipo de documento
research article
Resumen
Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
Palabras clave
MESH
Neoplasm Staging | Male | Young Adult | Neoplasms, Germ Cell and Embryonal | Spain | Adult | Testicular Neoplasms | Risk Factors | Humans | Adolescent | Practice Guidelines as Topic
DECS
Guías de Práctica Clínica como Asunto | Factores de Riesgo | Humanos | Adulto Joven | Estadificación de Neoplasias | Neoplasias Testiculares | Adulto | Neoplasias de Células Germinales y Embrionarias | España | Adolescente | Masculino
Versión en línea
DOI
Aparece en las colecciones
- Investigación > IIS > IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
- Investigación > IIS > IBIS - Instituto de Biomedicina de Sevilla (Andalucía)
- Investigación > IIS > IDIBELL - Instituto de Investigación Biomédica de Bellvitge (Cataluña)
- Investigación > IIS > IMIB - Instituto Murciano de Investigación Biosanitaria Pascual Parrilla (Murcia)
Acceso a texto completo