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dc.contributor.author | Balcells, Eva | |
dc.contributor.author | Gimeno-Santos, Elena | |
dc.contributor.author | de Batlle, Jordi | |
dc.contributor.author | Antonia Ramon, Maria | |
dc.contributor.author | Rodriguez, Esther | |
dc.contributor.author | Benet, Marta | |
dc.contributor.author | Farrero, Eva | |
dc.contributor.author | Ferrer, Antoni | |
dc.contributor.author | Guerra, Stefano | |
dc.contributor.author | Ferrer, Jaume | |
dc.contributor.author | Sauleda, Jaume | |
dc.contributor.author | Barbera, Joan A. | |
dc.contributor.author | Agusti, Alvar | |
dc.contributor.author | Rodriguez-Roisin, Robert | |
dc.contributor.author | Gea, Joaquim | |
dc.contributor.author | Anto, Josep M. | |
dc.contributor.author | Garcia-Aymerich, Judith | |
dc.contributor.author | PAC-COPD Study Grp | |
dc.date.accessioned | 2024-07-04T12:54:52Z | |
dc.date.available | 2024-07-04T12:54:52Z | |
dc.date.issued | 2015-01-17 | |
dc.identifier.citation | Balcells E, Gimeno-Santos E, De Batlle J, Ramon MA, Rodriguez E, Benet M, et al. Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation. BMC Pulm Med. 2015 Jan 17;15:4. | en |
dc.identifier.issn | 1471-2466 | |
dc.identifier.other | http://hdl.handle.net/20.500.13003/10968 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20095 | |
dc.description.abstract | Background: Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods: The PAC-COPD cohort included 342 COPD patients hospitalised for the first time for an exacerbation of COPD (2004-2006). Patients were extensively characterised using sociodemographic, clinical and functional variables, and the cohort was followed-up through 2008. We defined undiagnosed COPD by the absence of any self-reported respiratory disease and regular use of any pharmacological respiratory treatment. Results: Undiagnosed COPD was present in 34% of patients. They were younger (mean age 66 vs. 68 years, p = 0.03), reported fewer symptoms (mMRC dyspnoea score, 2.1 vs. 2.6, p < 0.01), and had a better health status (SGRQ total score, 29 vs. 40, p < 0.01), milder airflow limitation (FEV1% ref., 59% vs. 49%, p < 0.01), and fewer comorbidities (two or more, 40% vs. 56%, p < 0.01) when compared with patients with an established COPD diagnosis. Three months after hospital discharge, 16% of the undiagnosed COPD patients had stopped smoking (vs. 5%, p = 0.019). During follow-up, annual hospitalisation rates were lower in undiagnosed COPD patients (0.14 vs. 0.25, p < 0.01); however, this difference disappeared after adjustment for severity. Mortality was similar in both groups. Conclusions: Undiagnosed COPD patients have less severe disease and lower risk of re-hospitalisation when compared with hospitalised patients with known COPD. | en |
dc.description.sponsorship | The PAC-COPD Study is funded by grants from Fondo de Investigacion Sanitaria (FIS PI020541), Ministry of Health, Spain; Agencia d'Avaluacio de Tecnologia i Recerca Mediques (AATRM 035/20/02), Catalonia Government; Spanish Society of Pneumology and Thoracic Surgery (SEPAR 2002/137); Catalan Foundation of Pneumology (FUCAP 2003 Beca Maria Rava); Red RESPIRA (RTIC C03/11); Red RCESP (RTIC C03/09); Fondo de Investigacion Sanitaria (PI052486); Fondo de Investigacion Sanitaria (PI052302); Fondo de Investigacion Sanitaria (PI060684); Fundacio La Marato de TV3 (num. 041110); and Novartis Farmaceutica, Spain. CIBERESP and CIBERES are funded by the Instituto de Salud Carlos III, Ministry of Health, Spain. No involvement of funding sources in the study design, the collection, analysis, and interpretation of data, the writing of the report, or in the decision to submit the article for publication. Researchers are independent from funders. | es_ES |
dc.language.iso | eng | en |
dc.publisher | BioMed Central (BMC) | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Pulmonary disease | en |
dc.subject | Chronic obstructive | en |
dc.subject | Hospitalisation | en |
dc.subject | Cohort studies | en |
dc.subject | Epidemiology | en |
dc.subject | Health services | en |
dc.subject.mesh | Aged | * |
dc.subject.mesh | Dyspnea | * |
dc.subject.mesh | Pulmonary Disease, Chronic Obstructive | * |
dc.subject.mesh | Follow-Up Studies | * |
dc.subject.mesh | Humans | * |
dc.subject.mesh | Health Status | * |
dc.subject.mesh | Forced Expiratory Volume | * |
dc.subject.mesh | Middle Aged | * |
dc.subject.mesh | Tobacco Use | * |
dc.subject.mesh | Longitudinal Studies | * |
dc.subject.mesh | Prognosis | * |
dc.subject.mesh | Hospitalization | * |
dc.subject.mesh | Male | * |
dc.subject.mesh | Self Report | * |
dc.subject.mesh | Severity of Illness Index | * |
dc.subject.mesh | Female | * |
dc.subject.mesh | Smoking Cessation | * |
dc.subject.mesh | Comorbidity | * |
dc.subject.mesh | Patient Discharge | * |
dc.subject.mesh | Surveys and Questionnaires | * |
dc.title | Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation | en |
dc.type | research article | en |
dc.rights.license | Attribution 4.0 International | * |
dc.identifier.pubmedID | 25595204 | es_ES |
dc.format.volume | 15 | es_ES |
dc.format.page | 4 | es_ES |
dc.identifier.doi | 10.1186/1471-2466-15-4 | |
dc.relation.publisherversion | https://dx.doi.org/10.1186/1471-2466-15-4 | en |
dc.identifier.journal | BMC Pulmonary Medicine | es_ES |
dc.rights.accessRights | open access | en |
dc.subject.decs | Comorbilidad | * |
dc.subject.decs | Femenino | * |
dc.subject.decs | Uso de Tabaco | * |
dc.subject.decs | Hospitalización | * |
dc.subject.decs | Masculino | * |
dc.subject.decs | Estudios de Seguimiento | * |
dc.subject.decs | Volumen Espiratorio Forzado | * |
dc.subject.decs | Enfermedad Pulmonar Obstructiva Crónica | * |
dc.subject.decs | Estudios Longitudinales | * |
dc.subject.decs | Humanos | * |
dc.subject.decs | Persona de Mediana Edad | * |
dc.subject.decs | Estado de Salud | * |
dc.subject.decs | Pronóstico | * |
dc.subject.decs | Anciano | * |
dc.subject.decs | Índice de Severidad de la Enfermedad | * |
dc.subject.decs | Encuestas y Cuestionarios | * |
dc.subject.decs | Disnea | * |
dc.subject.decs | Alta del Paciente | * |
dc.subject.decs | Autoinforme | * |
dc.subject.decs | Cese del Hábito de Fumar | * |
dc.identifier.scopus | 2-s2.0-84925234718 | |
dc.identifier.wos | 350588200001 | |
dc.identifier.pui | L603143372 |
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