Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/20010
Título
How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry
Autor(es)
Fecha de publicación
2014-09
Cita
Sabater S, Berenguer R, Honrubia-Gomez P, Rivera M, Nunez A, Jimenez-Jimenez E, et al. How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry. J Radiat Res. 2014 Sep;55(5):1009-14. Epub 2014 Apr 10.
Idioma
Inglés
Tipo de documento
research article
Resumen
Radiation of experimental culture cells on plates with various wells can cause a risk of underdosage as a result of the existence of multiple air-water interfaces. The objective of our study was to quantify this error in culture plates with multiple wells. Radiation conditions were simulated with the GAMOS code, based on the GEANT4 code, and this was compared with a simulation performed with PENELOPE and measured data. We observed a slight underdosage of similar to 4% on the most superficial half of the culture medium. We believe that this underdosage does not have a significant effect on the dose received by culture cells deposited in a monolayer and adhered to the base of the wells.
Palabras clave
MESH
Cell Culture Techniques | Absorption, Radiation | Cell Physiological Phenomena | Equipment Design | Monte Carlo Method | Animals | Humans | Models, Statistical | Air | Equipment Failure Analysis | Scattering, Radiation | Computer Simulation
DECS
Modelos Estadísticos | Animales | Simulación por Computador | Análisis de Falla de Equipo | Humanos | Aire | Fenómenos Fisiológicos Celulares | Absorción de Radiación | Diseño de Equipo | Dispersión de Radiación | Método de Montecarlo | Técnicas de Cultivo de Célula
Versión en línea
DOI
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