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dc.contributor.authorSabater, Sebastia
dc.contributor.authorBerenguer, Roberto
dc.contributor.authorHonrubia-Gomez, Paloma
dc.contributor.authorRivera, Miguel
dc.contributor.authorNunez, Ana
dc.contributor.authorJiménez-Jiménez, Esther
dc.contributor.authorMartos, Ana
dc.contributor.authorRamirez-Castillejo, Carmen
dc.date.accessioned2024-07-03T11:09:32Z
dc.date.available2024-07-03T11:09:32Z
dc.date.issued2014-09
dc.identifier.citationSabater S, Berenguer R, Honrubia-Gomez P, Rivera M, Nunez A, Jimenez-Jimenez E, et al. How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry. J Radiat Res. 2014 Sep;55(5):1009-14. Epub 2014 Apr 10.en
dc.identifier.issn0449-3060
dc.identifier.otherhttp://hdl.handle.net/20.500.13003/11135
dc.identifier.urihttp://hdl.handle.net/20.500.12105/20010
dc.description.abstractRadiation of experimental culture cells on plates with various wells can cause a risk of underdosage as a result of the existence of multiple air-water interfaces. The objective of our study was to quantify this error in culture plates with multiple wells. Radiation conditions were simulated with the GAMOS code, based on the GEANT4 code, and this was compared with a simulation performed with PENELOPE and measured data. We observed a slight underdosage of similar to 4% on the most superficial half of the culture medium. We believe that this underdosage does not have a significant effect on the dose received by culture cells deposited in a monolayer and adhered to the base of the wells.en
dc.description.sponsorshipThis work was partially supported by Research Grant AN-2010/16 from Fundacion Sociosanitaria de Castilla-La Mancha (FISCAM). Funding to pay the Open Access publication charges for this article were provided by Junta local de Albacete de la Asociacion Espanola Contra el Cancer (AECC).es_ES
dc.language.isoengen
dc.publisherOxford University Press en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectMonte Carlo
dc.subjectPlate irradiation
dc.subjectCulture cells
dc.subject.meshCell Culture Techniques *
dc.subject.meshAbsorption, Radiation *
dc.subject.meshCell Physiological Phenomena *
dc.subject.meshEquipment Design *
dc.subject.meshMonte Carlo Method *
dc.subject.meshAnimals *
dc.subject.meshHumans *
dc.subject.meshModels, Statistical *
dc.subject.meshAir *
dc.subject.meshEquipment Failure Analysis *
dc.subject.meshScattering, Radiation *
dc.subject.meshComputer Simulation *
dc.titleHow air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometryen
dc.typeresearch articleen
dc.rights.licenseAttribution 4.0 International*
dc.identifier.pubmedID24722683es_ES
dc.format.volume55es_ES
dc.format.number5es_ES
dc.format.page1009-1014es_ES
dc.identifier.doi10.1093/jrr/rru022
dc.identifier.e-issn1349-9157es_ES
dc.relation.publisherversionhttps://dx.doi.org/10.1093/jrr/rru022en
dc.identifier.journalJournal of Radiation Researches_ES
dc.rights.accessRightsopen accessen
dc.subject.decsModelos Estadísticos*
dc.subject.decsAnimales*
dc.subject.decsSimulación por Computador*
dc.subject.decsAnálisis de Falla de Equipo*
dc.subject.decsHumanos*
dc.subject.decsAire*
dc.subject.decsFenómenos Fisiológicos Celulares*
dc.subject.decsAbsorción de Radiación*
dc.subject.decsDiseño de Equipo*
dc.subject.decsDispersión de Radiación*
dc.subject.decsMétodo de Montecarlo*
dc.subject.decsTécnicas de Cultivo de Célula*
dc.identifier.scopus2-s2.0-84908155004
dc.identifier.wos342223100021
dc.identifier.puiL605507452


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