Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/17884
Title
Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk.
Author(s)
Julibert, Alicia | Bibiloni, Maria Del Mar | Bouzas, Cristina | Martínez-González, Miguel Ángel | Salas-Salvadó, Jordi | Corella, Dolores | Zomeño, Maria Dolors | Romaguera, Dora | Vioque, Jesús | Alonso-Gómez, Ángel M | Wärnberg, Julia | Martínez, J Alfredo | Serra-Majem, Luís | Estruch, Ramon | Tinahones, Francisco J | Lapetra, José | Pintó, Xavier | Lopez-Miranda, José | García-Molina, Laura | Gaforio, José Juan | Matía-Martín, Pilar | Daimiel, Lidia | Martín-Sánchez, Vicente | Vidal, Josep | Vázquez, Clotilde | Ros, Emili | Toledo, Estefanía | Becerra-Tomás, Nerea | Pórtoles, Olga | Pérez-Vega, Karla A | Fiol, Miquel | Torres-Collado, Laura | Tojal-Sierra, Lucas | Carabaño-Moral, Rosa | Abete, Itziar | Sanchez-Villegas, Almudena | Casas, Rosa | Bernal-López, María Rosa | Santos-Lozano, José Manuel | Galera, Ana | Ugarriza, Lucía | Ruiz-Canela, Miguel | Babio, Nancy | Coltell, Oscar | Schröder, Helmut | Konieczna, Jadwiga | Orozco-Beltrán, Domingo | Sorto-Sánchez, Carolina | Eguaras, Sonia | Barrubés, Laura | Fitó, Montserrat | Tur, Josep A | Predimed-Plus Investigators
Date issued
2019-06-29
Language
Inglés
Document type
research article
Abstract
Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.
Subject
MESH
Aged | Biomarkers | Blood Glucose | Cardiovascular Diseases | Cross-Sectional Studies | Diet, Mediterranean | Dietary Fats | Dyslipidemias | Female | Humans | Hyperglycemia | Lipids | Male | Metabolic Syndrome | Middle Aged | Risk Assessment | Risk Factors | Spain | Treatment Outcome
DOI
Collections
- Investigación > IIS > IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
- Investigación > IIS > IMIBIC - Instituto Maimónides de Investigación Biomédica de Córdoba (Andalucía)
- Investigación > IIS > IMIM - Hospital del Mar Research Institute-Barcelona (Cataluña)
- Investigación > IIS > IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
- Investigación > IIS > IBIMA-Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (Andalucía)
- Investigación > IIS > IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)
- Investigación > IIS > IdISSC - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (Madrid)
- Investigación > IIS > ISABIAL - Instituto de Investigación de Sanitaria y Biomédica de Alicante (C. Valenciana)
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