Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/11751
Título
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study.
Autor(es)
Alonso-Molero, Jéssica | Dierssen-Sotos, Trinidad | Gomez-Acebo, Ines | Fernandez de Larrea-Baz, Nerea ISCIII | Guevara, Marcela | Amiano, Pilar | Castaño-Vinyals, Gemma | Fernandez-Villa, Tania | Moreno, Victor | Bayo, Juan | Molina-Barceloa, Ana | Fernández-Ortíz, María | Suarez-Calleja, Claudia | Marcos-Gragera, Rafael | Castells, Xavier | Gil-Majuelo, Leire | Ardanaz, Eva | Perez-Gomez, Beatriz ISCIII | Kogevinas, Manolis | Pollan-Santamaria, Marina ISCIII | Llorca, Javier
Fecha de publicación
2020
Cita
Int J Environ Res Public Health . 2020 Nov 13;17(22):8411.
Idioma
Inglés
Tipo de documento
journal article
Resumen
Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017-2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run.
Palabras clave
Versión en línea
DOI
Aparece en las colecciones
- Investigación > IIS > IDIVAL - Instituto de Investigación Marqués de Valdecilla (Cantabria)
- Investigación > IIS > IIS BioGipuzkoa - Asociación Instituto de Investigación Sanitaria BioGipuzkoa (País Vasco)
- Investigación > IIS > IMIM - Hospital del Mar Research Institute-Barcelona (Cataluña)
- Investigación > ISCIII > Centro Nacional de Epidemiología (CNE)
- Investigación > IIS > IDIBELL - Instituto de Investigación Biomédica de Bellvitge (Cataluña)
- Investigación > IIS > IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)