Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/9280
Título
A four-year survey (2011-2014) of West Nile virus infection in humans, mosquitoes and birds, including the 2012 meningoencephalitis outbreak in Tunisia
Autor(es)
Fecha de publicación
2018-03-14
Cita
Emerg Microbes Infect. 2018 Mar 14;7(1):28.
Idioma
Inglés
Tipo de documento
journal article
Resumen
A West Nile virus (WNV) outbreak occurred in Tunisia between mid-July and December 2012. To assess the epidemiological features of the WNV transmission cycle, human cerebrospinal fluid samples from patients with suspected cases (n = 79), Culex pipiens mosquitoes (n = 583) and serum specimens from domestic and migratory birds (n = 70) were collected for 4 years (2011-2014) in the Tunisian Sahel region. Viral testing was performed by polymerase chain reaction (PCR). The WNV genome was detected in 7 patients (8.8%), 4 Culex pipiens pools, and a domestic mallard (Anas platyrhynchos). All PCR-positive samples were from the Monastir region. Phylogenetic analysis revealed that two different WNV strain groups circulated, and isolates from the reservoir (bird), vector (Culex pipiens), and dead-end hosts (humans) were closely related. The Monastir region is a hot-spot for WNV infection, and the reiterative presence of WNV over the years has increased the risk of viral reemergence in Tunisia, which highlights the need for more enhanced and effective WNV surveillance in humans with public awareness campaigns strengthened by monitoring mosquitoes and maintaining avian surveillance for early detection of WNV circulation.
MESH
Adolescent | Adult | Aged | Animals | Bird Diseases | Birds | Cerebrospinal Fluid | Child | Child, Preschool | Culex | Disease Outbreaks | Female | Humans | Infant | Male | Meningoencephalitis | Middle Aged | Mosquito Vectors | Phylogeny | Tunisia | West Nile Fever | West Nile virus | Young Adult
Versión en línea
DOI
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