Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/8709
Título
New species genetic approach to identify strains of mitis group streptococci that are donors of rifampin resistance to Streptococcus pneumoniae
Autor(es)
Ferrandiz-Avellano, Maria-Jose ISCIII | Ardanuy, Carmen | Liñares, Josefina | Balsalobre-Arenas, Maria Luz ISCIII | Garcia, Maria Teresa ISCIII | de la Campa, Adela G ISCIII
Fecha de publicación
2011-01
Cita
Antimicrob Agents Chemother. 2011 Jan;55(1):368-72. doi: 10.1128/AAC.00856-10. Epub 2010 Nov 1.
Idioma
Inglés
Tipo de documento
journal article
Resumen
Eight rifampin-resistant streptococci of the mitis group were identified at the species level by using a concatenated 16S rRNA gene-sodA-rpoB-hlpA sequence. Characterization of their rpoB alleles showed single amino acid changes involved in rifampin resistance. Comparison of RpoB sequences from pneumococcal recombinant isolates, viridans isolates, and type strains revealed a species-specific amino acid signature, which allowed it to be ascertained that recombinant RpoBs were originated in genetic interchanges with Streptococcus mitis and Streptococcus oralis.
MESH
Anti-Bacterial Agents | Drug Resistance, Bacterial | Phylogeny | RNA, Ribosomal, 16S | Rifampin | Streptococcus mitis | Streptococcus oralis | Streptococcus pneumoniae
Versión en línea
DOI
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