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dc.contributor.authorUsme-Ciro, Jose A
dc.contributor.authorMendez, Jairo A
dc.contributor.authorTenorio, Antonio 
dc.contributor.authorRey, Gloria J
dc.contributor.authorDomingo, Cristina 
dc.contributor.authorGallego-Gomez, Juan C
dc.identifier.citationVirol J. 2008 Sep 2;5:101.es_ES
dc.description.abstractBACKGROUND: Dengue is a major health problem in tropical and subtropical regions. In Colombia, dengue viruses (DENV) cause about 50,000 cases annually, 10% of which involve Dengue Haemorrhagic Fever/Dengue Shock Syndrome. The picture is similar in other surrounding countries in the Americas, with recent outbreaks of severe disease, mostly associated with DENV serotype 3, strains of the Indian genotype, introduced into the Americas in 1994. RESULTS: The analysis of the 3'end (224 bp) of the envelope gene from 32 DENV-3 strains recently recovered in Colombia confirms the circulation of the Indian genotype, and surprisingly the co-circulation of an Asian-Pacific genotype only recently described in the Americas. CONCLUSION: These results have important implications for epidemiology and surveillance of DENV infection in Central and South America. Molecular surveillance of the DENV genotypes infecting humans could be a very valuable tool for controlling/mitigating the impact of the DENV infection.es_ES
dc.description.sponsorshipThis research was supported by Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología Francisco José de Caldas – COLCIENCIAS grant 11150416336 CT 234–2004 from the Colombian government and CODI E00943 from the Universidad de Antioquia.es_ES
dc.publisherBiomed Centrales_ES
dc.relation.isversionofPublisher's versiones_ES
dc.subject.meshColombia es_ES
dc.subject.meshDengue Virus es_ES
dc.subject.meshGenetic Variation es_ES
dc.subject.meshGenotype es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMolecular Epidemiology es_ES
dc.subject.meshPhylogeny es_ES
dc.subject.meshSevere Dengue es_ES
dc.titleSimultaneous circulation of genotypes I and III of dengue virus 3 in Colombiaes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderInstituto Colombiano para el Desarrollo de la Ciencia y la Tecnología Francisco José de Caldas (COLCIENCIAS)es_ES
dc.contributor.funderUniversidad de Antioquiaes_ES
dc.identifier.journalVirology journales_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES

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Atribución 4.0 Internacional
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