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dc.contributor.authorUsme-Ciro, Jose A
dc.contributor.authorMendez, Jairo A
dc.contributor.authorTenorio, Antonio 
dc.contributor.authorRey, Gloria J
dc.contributor.authorDomingo Carrasco, Cristina 
dc.contributor.authorGallego-Gomez, Juan C
dc.date.accessioned2019-03-06T13:59:24Z
dc.date.available2019-03-06T13:59:24Z
dc.date.issued2008-09-02
dc.identifier.citationVirol J. 2008 Sep 2;5:101.es_ES
dc.identifier.issn1743-422Xes_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7291
dc.description.abstractBACKGROUND: Dengue is a major health problem in tropical and subtropical regions. In Colombia, dengue viruses (DENV) cause about 50,000 cases annually, 10% of which involve Dengue Haemorrhagic Fever/Dengue Shock Syndrome. The picture is similar in other surrounding countries in the Americas, with recent outbreaks of severe disease, mostly associated with DENV serotype 3, strains of the Indian genotype, introduced into the Americas in 1994. RESULTS: The analysis of the 3'end (224 bp) of the envelope gene from 32 DENV-3 strains recently recovered in Colombia confirms the circulation of the Indian genotype, and surprisingly the co-circulation of an Asian-Pacific genotype only recently described in the Americas. CONCLUSION: These results have important implications for epidemiology and surveillance of DENV infection in Central and South America. Molecular surveillance of the DENV genotypes infecting humans could be a very valuable tool for controlling/mitigating the impact of the DENV infection.es_ES
dc.description.sponsorshipThis research was supported by Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología Francisco José de Caldas – COLCIENCIAS grant 11150416336 CT 234–2004 from the Colombian government and CODI E00943 from the Universidad de Antioquia.es_ES
dc.language.isoenges_ES
dc.publisherBioMed Central (BMC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshColombia es_ES
dc.subject.meshDengue Virus es_ES
dc.subject.meshGenetic Variation es_ES
dc.subject.meshGenotype es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMolecular Epidemiology es_ES
dc.subject.meshPhylogeny es_ES
dc.subject.meshSevere Dengue es_ES
dc.titleSimultaneous circulation of genotypes I and III of dengue virus 3 in Colombiaes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID18764951es_ES
dc.format.volume5es_ES
dc.format.number1es_ES
dc.format.page101es_ES
dc.identifier.doi10.1186/1743-422X-5-101es_ES
dc.contributor.funderColciencias 
dc.contributor.funderUniversity of Antioquia (Colombia) 
dc.description.peerreviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1186/1743-422X-5-101es_ES
dc.identifier.journalVirology journales_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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