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dc.contributor.author | Hernando Sebastian, Victoria | |
dc.contributor.author | Alejos, Belén | |
dc.contributor.author | Monge Corella, Susana | |
dc.contributor.author | Berenguer, Juan | |
dc.contributor.author | Anta, Lourdes | |
dc.contributor.author | Vinuesa, David | |
dc.contributor.author | Palacios, Rosario | |
dc.contributor.author | Muga, Roberto | |
dc.contributor.author | Moreno, Santiago | |
dc.contributor.author | Jarrin-Vera, Inmaculada | |
dc.date.accessioned | 2019-02-01T14:11:16Z | |
dc.date.available | 2019-02-01T14:11:16Z | |
dc.date.issued | 2013-08-20 | |
dc.identifier.citation | BMC Infect Dis. 2013 Aug 20;13:382. | es_ES |
dc.identifier.issn | 1471-2334 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/7061 | |
dc.description.abstract | BACKGROUND: Combination antiretroviral therapy (cART) has produced significant changes in mortality of HIV-infected persons. Our objective was to estimate mortality rates, standardized mortality ratios and excess mortality rates of cohorts of the AIDS Research Network (RIS) (CoRIS-MD and CoRIS) compared to the general population. METHODS: We analysed data of CoRIS-MD and CoRIS cohorts from 1997 to 2010. We calculated: (i) all-cause mortality rates, (ii) standardized mortality ratio (SMR) and (iii) excess mortality rates for both cohort for 100 person-years (py) of follow-up, comparing all-cause mortality with that of the general population of similar age and gender. RESULTS: Between 1997 and 2010, 8,214 HIV positive subjects were included, 2,453 (29.9%) in CoRIS-MD and 5,761 (70.1%) in CoRIS and 294 deaths were registered. All-cause mortality rate was 1.02 (95% CI 0.91-1.15) per 100 py, SMR was 6.8 (95% CI 5.9-7.9) and excess mortality rate was 0.8 (95% CI 0.7-0.9) per 100 py. Mortality was higher in patients with AIDS, hepatitis C virus (HCV) co-infection, and those from CoRIS-MD cohort (1997-2003). CONCLUSION: Mortality among HIV-positive persons remains higher than that of the general population of similar age and sex, with significant differences depending on the history of AIDS or HCV coinfection. | es_ES |
dc.description.sponsorship | The RIS cohort (CoRIS) is funded by the Instituto de Salud Carlos III through the Red Temática de Investigación Cooperativa en sida (RIS C03/173). This work has been partially funded by a grant from the FIS (Spanish Networks for Research on AIDS and Public Health), 04/0900 and RIS (Spanish HIV Research Network for excellence) RD06/0006. Susana Monge has been granted by Rio Ortega program (º exp CM10/00154). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central (BMC) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | Acquired Immunodeficiency Syndrome | es_ES |
dc.subject.mesh | Adult | es_ES |
dc.subject.mesh | Cohort Studies | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Middle Aged | es_ES |
dc.subject.mesh | Risk Factors | es_ES |
dc.subject.mesh | Spain | es_ES |
dc.subject.mesh | Young Adult | es_ES |
dc.title | All-cause mortality in the cohorts of the Spanish AIDS Research Network (RIS) compared with the general population: 1997-2010 | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 23961924 | es_ES |
dc.format.volume | 13 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 382 | es_ES |
dc.identifier.doi | 10.1186/1471-2334-13-382 | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1471-2334 | es_ES |
dc.relation.publisherversion | https://doi.org/10.1186/1471-2334-13-382 | es_ES |
dc.identifier.journal | BMC infectious diseases | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Epidemiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/04/0900 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RD06/0006 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RIS C03/173 | es_ES |
dc.rights.accessRights | open access | es_ES |