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dc.contributor.author | Pedro-Cuesta, Jesus de | |
dc.contributor.author | Glatzel, Markus | |
dc.contributor.author | Almazan-Isla, Javier | |
dc.contributor.author | Stoeck, Katharina | |
dc.contributor.author | Mellina, Vittorio | |
dc.contributor.author | Puopolo, Maria | |
dc.contributor.author | Pocchiari, Maurizio | |
dc.contributor.author | Zerr, Inga | |
dc.contributor.author | Kretszchmar, Hans A | |
dc.contributor.author | Brandel, Jean-Philippe | |
dc.contributor.author | Delasnerie-Lauprêtre, Nicole | |
dc.contributor.author | Alpérovitch, Annick | |
dc.contributor.author | Van Duijn, Cornelia | |
dc.contributor.author | Sánchez-Juan, Pascual | |
dc.contributor.author | Collins, Steven | |
dc.contributor.author | Lewis, Victoria | |
dc.contributor.author | Jansen, Gerard H | |
dc.contributor.author | Coulthart, Michael B | |
dc.contributor.author | Gelpi, Ellen | |
dc.contributor.author | Budka, Herbert | |
dc.contributor.author | Mitrova, Eva | |
dc.date.accessioned | 2019-01-31T10:46:43Z | |
dc.date.available | 2019-01-31T10:46:43Z | |
dc.date.issued | 2006-11-10 | |
dc.identifier.citation | BMC Public Health. 2006 Nov 10;6:278. | es_ES |
dc.identifier.issn | 1471-2458 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/7046 | |
dc.description.abstract | BACKGROUND: The objective of this study was to describe the diagnostic panorama of human transmissible spongiform encephalopathies across 11 countries. METHODS: From data collected for surveillance purposes, we describe annual proportions of deaths due to different human transmissible spongiform encephalopathies in eleven EUROCJD-consortium countries over the period 1993-2002, as well as variations in the use of diagnostic tests. Using logistic models we quantified international differences and changes across time. RESULTS: In general, pre-mortem use of diagnostic investigations increased with time. International differences in pathological confirmation of sporadic Creutzfeldt-Jakob disease, stable over time, were evident. Compared to their counterparts, some countries displayed remarkable patterns, such as: 1) the high proportion, increasing with time, of variant Creutzfeldt-Jakob disease in the United Kingdom, (OR 607.99 95% CI 84.72-4363.40), and France (OR 18.35, 95% CI 2.20-152.83); 2) high, decreasing proportions of iatrogenic Creutzfeldt-Jakob disease in France, (OR 5.81 95% CI 4.09-8.24), and the United Kingdom, (OR 1.54 95% CI 1.03-2.30); and, 3) high and stable ratios of genetic forms in Slovakia (OR 21.82 95% CI 12.42-38.33) and Italy (OR 2.12 95% CI 1.69-2.68). CONCLUSION: Considerable international variation in aetiological subtypes of human transmissible spongiform encephalopathies was evident over the observation period. With the exception of variant Creutzfeldt-Jakob disease and iatrogenic Creutzfeldt-Jakob disease in France and the United Kingdom, these differences persisted across time. | es_ES |
dc.description.sponsorship | This study was funded through NeuroPrion, an EU Network of Excellence funded by Framework 6 Programme, Contract number: FOOD CT 2004 056579, and EUROCJD funded by DG SANCO; Contract number: 2003201 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central (BMC) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | Australia | es_ES |
dc.subject.mesh | Canada | es_ES |
dc.subject.mesh | Creutzfeldt-Jakob Syndrome | es_ES |
dc.subject.mesh | Cross-Cultural Comparison | es_ES |
dc.subject.mesh | Electroencephalography | es_ES |
dc.subject.mesh | Europe | es_ES |
dc.subject.mesh | France | es_ES |
dc.subject.mesh | Genotype | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Iatrogenic Disease | es_ES |
dc.subject.mesh | Internationality | es_ES |
dc.subject.mesh | Italy | es_ES |
dc.subject.mesh | Magnetic Resonance Imaging | es_ES |
dc.subject.mesh | Population Surveillance | es_ES |
dc.subject.mesh | Prion Proteins | es_ES |
dc.subject.mesh | Prions | es_ES |
dc.subject.mesh | Registries | es_ES |
dc.subject.mesh | Slovakia | es_ES |
dc.subject.mesh | Time | es_ES |
dc.subject.mesh | United Kingdom | es_ES |
dc.title | Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002 | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 17096829 | es_ES |
dc.format.volume | 6 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 278 | es_ES |
dc.identifier.doi | 10.1186/1471-2458-6-278 | es_ES |
dc.contributor.funder | Unión Europea. Comisión Europea. 6 Programa Marco | |
dc.description.peerreviewed | Sí | es_ES |
dc.relation.publisherversion | https://doi.org/10.1186/1471-2458-6-278 | es_ES |
dc.identifier.journal | BMC public health | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Epidemiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP6/FOOD CT 2004 056579 | es_ES |
dc.rights.accessRights | open access | es_ES |