Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/20274
Título
Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study
Autor(es)
Lassale, Camille | Gunter, Marc J | Romaguera, Dora | Peelen, Linda M | Van der Schouw, Yvonne T | Beulens, Joline WJ | Freisling, Heinz | Muller, David C | Ferrari, Pietro | Huybrechts, Inge | Fagherazzi, Guy | Boutron-Ruault, Marie-Christine | Affret, Aurelie | Overvad, Kim | Dahm, Christina Catherine | Olsen, Anja | Roswall, Nina | Tsilidis, Konstantinos K | Katzke, Verena A | Kuehn, Tilman | Buijsse, Brian | Quiros, Jose-Ramon | Sanchez-Cantalejo, Emilio | Etxezarreta, Nerea | Maria Huerta, Jose | Barricarte, Aurelio | Bonet, Catalina | Khaw, Kay-Tee | Key, Timothy J | Trichopoulou, Antonia | Bamia, Christina | Lagiou, Pagona | Palli, Domenico | Agnoli, Claudia | Tumino, Rosario | Fasanelli, Francesca | Panico, Salvatore | Bueno-de-Mesquita, H. Bas | Boer, Jolanda M. A | Sonestedt, Emily | Nilsson, Lena Maria | Renstrom, Frida | Weiderpass, Elisabete | Skeie, Guri | Lund, Eiliv | Moons, Karel G. M | Riboli, Elio | Tzoulaki, Ioanna
Fecha de publicación
2016-07-13
Cita
Lassale C, Gunter MJ, Romaguera D, Peelen LM, Van Der Schouw YT, Beulens Joline WJ, et al. Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study. PLoS One. 2016 Jul 13;11(7):e0159025.
Idioma
Inglés
Tipo de documento
research article
Resumen
Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.
MESH
Cardiovascular Diseases | European Continental Ancestry Group | Humans | Life Style | Middle Aged | Neoplasms | Diet | Male | Female | Risk Factors | Age Distribution | Sex Distribution | Cohort Studies
DECS
Distribución por Edad | Estudios de Cohortes | Distribución por Sexo | Femenino | Dieta | Grupo de Ascendencia Continental Europea | Masculino | Factores de Riesgo | Humanos | Persona de Mediana Edad | Neoplasias | Estilo de Vida | Enfermedades Cardiovasculares
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