dc.contributor.author | Larranaga, Nerea | |
dc.contributor.author | Jose Sanchez, Ma | |
dc.contributor.author | Ardanaz, Eva | |
dc.contributor.author | Felipe, Saray | |
dc.contributor.author | Marcos-Gragera, Rafael | |
dc.contributor.author | Ramos Monserrat, Maria | |
dc.contributor.author | Carulla, Maria | |
dc.contributor.author | Chirlaque, Maria-Dolores | |
dc.contributor.author | Argueelles, Marcial V | |
dc.contributor.author | Martos, Carmen | |
dc.contributor.author | Mateo, Antonio | |
dc.contributor.author | Peris-Bonet, Rafael | |
dc.date.accessioned | 2024-07-09T09:13:01Z | |
dc.date.available | 2024-07-09T09:13:01Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Larranaga N, Sanchez MJ, Ardanaz E, Felipe S, Marcos-Gragera R, Ramos Monserrat M, et al. Incidence Patterns and Trends of non-Central Nervous System Solid Tumours in Children and Adolescents. A Collaborative Study of the Spanish Population Based Cancer Registries. J Cancer. 2016;7(3):335-43. | en |
dc.identifier.issn | 1837-9664 | |
dc.identifier.other | http://hdl.handle.net/20.500.13003/17183 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20237 | |
dc.description.abstract | Objective: To describe incidence patterns and trends in children (0-14 years) and adolescents (15-19 age-range) with solid tumours, except those of central nervous system (CNS), in Spain. Methods: Cases were drawn from eleven Spanish population-based cancer registries. Incidence was estimated for the period 1983-2007 and trends were evaluated using Joinpoint regression analysis. Results: The studied tumour groups accounted for 36% of total childhood cancers and 47.6% of those diagnosed in adolescence with annual rates per million of 53.5 and 89.3 respectively. In children 0 to 14 years of age, Neuroblastoma (NB) was the commonest (7.8%) followed by Soft-tissue sarcomas (STS) (6.3%), bone tumours (BT) (6.2%) and renal tumours (RT) (4.5%). NB was the most frequently diagnosed tumour before the 5th birthday, while STS and BT were the commonest at 5-9 years of age, and BT and Carcinoma and other epithelial tumours (COET) at 10-14. COET presented the highest incidence in adolescents, followed by germ-cell tumours (GCT), BT and STS. These four diagnostic groups accounted for 94% of total non-CNS solid tumours, in adolescents. Overall incidence rates increased significantly in children up to 1996 with an annual percentage change (APC) of 2.6% (95% CI: 1.7; 3.6). NB and COET showed significant time trend (APCs: 1.4% and 3.8% respectively) while other tumour groups such as RT, STS, BT or GCT had no significant changes over time. A significant increase was present in NB under the age of 5 and in BT and STS in children aged 10-14 years. In adolescents there were significant increases for all tumours combined (APC=2.7; 95% CI: 1.8-3.6) and for STS, GCT and COET (APCs: 3.2%, 4.4% and 3.5% respectively), while other tumour groups such as hepatic tumours, BT or thyroid carcinomas showed a decreasing trend or no increase. Conclusions: Overall, the incidence of the studied cancers in children increased along the period 1983-1996 with no posterior significant rise, while the incidence in adolescents increased significantly over the whole period 1983-2007. Several specific tumour groups showed significant rises or decrements in childhood or adolescence, although the small number of cases precludes showing significant trends or inflexion points. | en |
dc.language.iso | eng | en |
dc.publisher | Ivyspring International Publisher | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Cancer | |
dc.subject | Solid tumour | |
dc.subject | Childhood | |
dc.subject | Adolescents | |
dc.subject | Population-based study | |
dc.subject | Incidence | |
dc.subject | Spain | |
dc.title | Incidence Patterns and Trends of non-Central Nervous System Solid Tumours in Children and Adolescents. A Collaborative Study of the Spanish Population Based Cancer Registries | en |
dc.type | research article | en |
dc.rights.license | Attribution-NonCommercial 4.0 International | * |
dc.identifier.pubmedID | 26918047 | es_ES |
dc.format.volume | 7 | es_ES |
dc.format.number | 3 | es_ES |
dc.format.page | 335-343 | es_ES |
dc.identifier.doi | 10.7150/jca.12943 | |
dc.relation.publisherversion | https://dx.doi.org/10.7150/jca.12943 | en |
dc.identifier.journal | Journal of Cancer | es_ES |
dc.rights.accessRights | open access | en |
dc.identifier.scopus | 2-s2.0-84971577855 | |
dc.identifier.wos | 370178400014 | |
dc.identifier.pui | L610558667 | |