Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/20009
Título
Treatment of prostate cancer according to life expectancy, comorbidity and clinical practice guidelines
Autor(es)
Fecha de publicación
2014-09
Cita
Barcelo Obrador A, Ramos M, De La Iglesia MT, Zaforteza M. Treatment of prostate cancer according to life expectancy, comorbidity and clinical practice guidelines. An Sist Sanit Navar. 2014 Sep;37(3):339-48.
Idioma
Español
Tipo de documento
research article
Resumen
Background. To describe the treatment of prostate cancer patients according to life expectancy, risk and comorbidity, to examine the degree to which Clinical Practice Guidelines (CPG) are followed, and to register secondary effects after one year. Methods. Retrospective study of patients diagnosed with prostate cancer in a hospital in 2011. Socio-demographic variables, as well as comorbidity (Charlson index), tumor characteristics, treatments and secondary effects were collected. A bivariate analysis was performed using the Chi square test. Results. One hundred and fourteen patients were identified. Life expectancy was higher than 10 years in 92.1%; 50% had low comorbidity, 36% medium and 14% high. Surgery was performed in 56.2%, more often in patients with intermediate-risk and low comorbidity; radiotherapy in 13.2%, more often in patients with high-risk and low comorbidity; hormonal therapy in 21.9%, more often in patients with medium comorbidity, and deferred treatment in 12.3%. CPG recommendations were not followed in 38.6%, especially in high-risk patients, 58.1%. Regarding adverse effects, 70% of patients treated with surgery presented urinary incontinence, and 48.3% erectile dysfunction. On the other hand, 17.15% of patients treated with hormonal therapy presented a cardiovascular disease, and 32.5% worsening of a cardiovascular risk factor. Conclusions. Treatment of prostate cancer takes into account risk and comorbidity, but there could be improvement in following CPG guidelines, especially in elderly patients. It is advisable to develop preventive strategies to avoid cardiovascular effects in patients with hormonal therapy.
Palabras clave
MESH
Aged, 80 and over | Aged | Male | Adult | Humans | Prostatic Neoplasms | Life Expectancy | Guideline Adherence | Middle Aged | Cross-Sectional Studies | Retrospective Studies
DECS
Estudios Transversales | Humanos | Esperanza de Vida | Persona de Mediana Edad | Anciano | Anciano de 80 o más Años | Estudios Retrospectivos | Adulto | Adhesión a Directriz | Neoplasias de la Próstata | Masculino
Versión en línea
DOI
Aparece en las colecciones
Acceso a texto completo