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Título
New GOLD classification: longitudinal data on group assignment
Autor(es)
Casanova, Ciro | Marin, Jose M | Martinez-Gonzalez, Cristina | de Lucas, Pilar | Mir-Viladrich, Isabel | García-Cosío, Borja | Peces-Barba, German | Calle-Rubio, Miryam | Solanes-Garcia, Ingrid | Agueero, Ramn | de Diego-Damia, Alfredo | Feu-Collado, Nuria | Alfageme, Inmaculada | Irigaray, Rosa | Balcells, Eva | Llunell, Antonia | Bautista Galdiz, Juan | Marin, Margarita | Jose Soler-Cataluna, Juan | Luis Lopez-Campos, Jose | Soriano, Joan B | de-Torres, Juan P | COPD Hist Assessment SpaiN CHAIN C
Fecha de publicación
2014-01-13
Cita
Casanova C, Marin JM, Martinez-Gonzalez C, De Lucas-Ramos P, Mir-Viladrich I, Cosio BG, et al. New GOLD classification: longitudinal data on group assignment. Respir Res. 2014 Jan 13;15:3.
Idioma
Inglés
Tipo de documento
research article
Resumen
Rationale: Little is known about the longitudinal changes associated with using the 2013 update of the multidimensional GOLD strategy for chronic obstructive pulmonary disease (COPD). Objective: To determine the COPD patient distribution of the new GOLD proposal and evaluate how this classification changes over one year compared with the previous GOLD staging based on spirometry only. Methods: We analyzed data from the CHAIN study, a multicenter observational Spanish cohort of COPD patients who are monitored annually. Categories were defined according to the proposed GOLD: FEV1%, mMRC dyspnea, COPD Assessment Test (CAT), Clinical COPD Questionnaire (CCQ), and exacerbations-hospitalizations. One-year follow-up information was available for all variables except CCQ data. Results: At baseline, 828 stable COPD patients were evaluated. On the basis of mMRC dyspnea versus CAT, the patients were distributed as follows: 38.2% vs. 27.2% in group A, 17.6% vs. 28.3% in group B, 15.8% vs. 12.9% in group C, and 28.4% vs. 31.6% in group D. Information was available for 526 patients at one year: 64.2% of patients remained in the same group but groups C and D show different degrees of variability. The annual progression by group was mainly associated with one-year changes in CAT scores (RR, 1.138; 95% CI: 1.074-1.206) and BODE index values (RR, 2.012; 95% CI: 1.487-2.722). Conclusions: In the new GOLD grading classification, the type of tool used to determine the level of symptoms can substantially alter the group assignment. A change in category after one year was associated with longitudinal changes in the CAT and BODE index.
Palabras clave
MESH
Aged | Spain | Pulmonary Disease, Chronic Obstructive | Follow-Up Studies | Humans | Middle Aged | Longitudinal Studies | Global Health | Male | Prospective Studies | Databases, Factual | Female | Cohort Studies
DECS
Estudios de Cohortes | Salud Global | Bases de Datos Factuales | Femenino | Masculino | Estudios de Seguimiento | Enfermedad Pulmonar Obstructiva Crónica | Estudios Longitudinales | Humanos | Persona de Mediana Edad | Estudios Prospectivos | Anciano | España
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