Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/19097
Title
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
Author(s)
Bassetti, Matteo | Giacobbe, Daniele R | Agvald-Ohman, Christina | Akova, Murat | Alastruey-Izquierdo, Ana ISCIII | Arikan-Akdagli, Sevtap | Azoulay, Elie | Blot, Stijn | Cornely, Oliver A | Cuenca-Estrella, Manuel ISCIII | de Lange, Dylan W | De Rosa, Francesco G | De Waele, Jan J | Dimopoulos, George | Garnacho-Montero, Jose | Hoenigl, Martin | Kanj, Souha S | Koehler, Philipp | Kullberg, Bart J | Lamoth, Frédéric | Lass-Flörl, Cornelia | Maertens, Johan | Martin-Loeches, Ignacio | Muñoz, Patricia | Poulakou, Garyphallia | Rello, Jordi | Sanguinetti, Maurizio | Taccone, Fabio S | Timsit, Jean-François | Torres, Antoni | Vazquez, Jose A | Wauters, Joost | Asperges, Erika | Cortegiani, Andrea | Grecchi, Cecilia | Karaiskos, Ilias | Le Bihan, Clément | Mercier, Toine | Mortensen, Klaus L | Peghin, Maddalena | Rebuffi, Chiara | Tejada, Sofia | Vena, Antonio | Zuccaro, Valentina | Scudeller, Luigia | Calandra, Thierry | Study Group for Infections in Critically Ill Patients of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP) | Fungal Infection Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG) | European Society of Intensive Care Medicine (ESICM) | European Confederation of Medical Mycology (ECMM) | Mycoses Study Group Education and Research Consortium (MSGERC) | International Society of Antimicrobial Chemotherapy (ISAC) | International Society for Human and Animal Mycology (ISHAM) | Austrian Society for Medical Mycology (ÖGMM) | Italian Society of Anesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI) | Italian Society of Anti-Infective Therapy (SITA) | FUNDICU Collaborators
Date issued
2024-03-21
Citation
Intensive Care Med. 2024 Apr;50(4):502-515.
Language
Inglés
Document type
research article
Abstract
Purpose: The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care units (ICUs). Methods: After a systematic assessment of the diagnostic performance for IFD in the target population of already existing definitions and laboratory tests, consensus definitions were developed by a panel of experts using the RAND/UCLA appropriateness method. Results: Standardized research definitions were developed for proven invasive candidiasis, probable deep-seated candidiasis, proven invasive aspergillosis, probable invasive pulmonary aspergillosis, and probable tracheobronchial aspergillosis. The limited evidence on the performance of existing definitions and laboratory tests for the diagnosis of IFD other than candidiasis and aspergillosis precluded the development of dedicated definitions, at least pending further data. The standardized definitions provided in the present document are aimed to speed-up the design, and increase the feasibility, of future comparative research studies.
Subject
Invasive fungal diseases | Aspergillus | Candida | Consensus | Definitions | Diagnosis | Intensive care unit | Research
Online version
DOI
Collections
- Investigación > IIS > IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
- Investigación > ISCIII > Centro Nacional de Microbiología (CNM)
- Investigación > IIS > IiSGM - Instituto de Investigación Sanitaria Gregorio Marañón (Madrid)
- Investigación > IIS > IR-HUVH - Instituto de Investigación Hospital Universitari Vall d’Hebron (Cataluña)
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