Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/17839
Title
Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk.
Author(s)
Papandreou, Christopher | Babio, Nancy | Díaz-López, Andrés | Martínez-González, Miguel Á | Becerra-Tomas, Nerea | Corella, Dolores | Schröder, Helmut | Romaguera, Dora | Vioque, Jesús | Alonso-Gómez, Ángel M | Wärnberg, Julia | Martínez, Alfredo J | Serra-Majem, Lluís | Estruch, Ramon | Muñoz-Garach, Araceli | Lapetra, José | Pintó, Xavier | Tur, Josep A | Garcia-Rios, Antonio | Bueno-Cavanillas, Aurora | Delgado-Rodríguez, Miguel | Matía-Martín, Pilar | Daimiel, Lidia | M Sánchez, Vicente | Vidal, Josep | Vázquez, Clotilde | Ros, Emilio | Ruiz-Canela, Miguel | Bulló, Mónica | Sorli, Jose V | Quifer, Mireia | Colom, Antoni | Oncina-Canovas, Alejandro | T Sierra, Lucas | Barón-López, Javier | Pérez-Farinós, Napoleón | Abete, Itziar | Sanchez-Villegas, Almudena | Casas, Rosa | F García, José C | Santos-Lozano, José M | Corbella, Emili | Del M Bibiloni, Maria | Diez-Espino, Javier | Asensio, Eva M | Torras, Laura | Morey, Marga | Compañ-Gabucio, Laura | S Lete, Itziar | Cenoz-Osinaga, Juan C | Castañer, Olga | Salas-Salvadó, Jordi
Date issued
2019-04-01
Language
Inglés
Document type
research article
Abstract
The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
Subject
MESH
Aged | Biomarkers | Cardiovascular Diseases | Creatinine | Cross-Sectional Studies | Female | Humans | Male | Mediterranean Region | Middle Aged | Risk Factors | Sleep | Spain | Uric Acid
DOI
Collections
- Investigación > IIS > IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
- Investigación > IIS > IMIBIC - Instituto Maimónides de Investigación Biomédica de Córdoba (Andalucía)
- Investigación > IIS > IMIM - Hospital del Mar Research Institute-Barcelona (Cataluña)
- Investigación > IIS > IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
- Investigación > IIS > IBIMA-Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (Andalucía)
- Investigación > IIS > IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)
- Investigación > IIS > IdISSC - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (Madrid)
- Investigación > IIS > ISABIAL - Instituto de Investigación de Sanitaria y Biomédica de Alicante (C. Valenciana)
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