Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/16259
Título
The circadian neutrophil, inside-out.
Autor(es)
Fecha de publicación
2023-06-01
Cita
J Leukoc Biol. 2023 Jun 1;113(6):555-566
Idioma
Inglés
Tipo de documento
review
Resumen
The circadian clock has sway on a myriad of physiological targets, among which the immune and inflammatory systems are particularly prominent. In this review, we discuss how neutrophils, the wildcard of the immune system, are regulated by circadian oscillations. We describe cell-intrinsic and extrinsic diurnal mechanisms governing the general physiology and function of these cells, from purely immune to homeostatic. Repurposing the concepts discovered in other cell types, we then speculate on various uncharted avenues of neutrophil-circadian relationships, such as topology, metabolism, and the regulation of tissue clocks, with the hope of identifying exciting new avenues of work in the context of circadian immunity.
MESH
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DOI
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- The circadian neutrophil J Leukoc ...
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