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Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/16073
Title
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Author(s)
Hanke, Leo | Das, Hrishikesh | Sheward, Daniel J. | Perez Vidakovics, Laura | Urgard, Egon | Moliner-Morro, Ainhoa | Kim, Changil | Karl, Vivien | Pankow, Alec | Smith, Natalie L. | Porebski, Bartlomiej | Fernandez-Capetillo, Oscar CNIO | Sezgin, Erdinc | Pedersen, Gabriel K. | Coquet, Jonathan M. | Hällberg, B. Martin | Murrell, Ben | McInerney, Gerald M.
Date issued
2022-01-13
Citation
Nat Commun. 2022;13(1):155.
Language
Inglés
Document type
journal article
MESH
Animals | Antibodies, Bispecific | Antibodies, Neutralizing | Antibodies, Viral | COVID-19 | Chlorocebus aethiops | Cryoelectron Microscopy | HEK293 Cells | Humans | Mice, Transgenic | Neutralization Tests | Protein Binding | Protein Conformation | Protein Multimerization | SARS-CoV-2 | Single-Domain Antibodies | Spike Glycoprotein, Coronavirus | Vero Cells
Online version
https://doi.org/10.1038/s41467-021-27610-z.
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