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A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer
A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity
Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors
Characterization of Novel Missense Variants of SERPINA1 Gene Causing Alpha-1 Antitrypsin Deficiency.
Deubiquitinase USP10 regulates Notch signaling in the endothelium
Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells
FAS system deregulation in T-cell lymphoblastic lymphoma
Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing
Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA
Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span
Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine
Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action
In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells.
Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction.
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense.
MicroRNA-661 modulates redox and metabolic homeostasis in colon cancer
Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions.