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dc.contributor.authorFernandez de Larrea, Nerea 
dc.contributor.authorPerez-Gomez, Beatriz 
dc.contributor.authorGuerrero-Zotano, Ángel
dc.contributor.authorCasas, Ana María
dc.contributor.authorBermejo, Begoña
dc.contributor.authorBaena-Cañada, José Manuel
dc.contributor.authorAntolín, Silvia
dc.contributor.authorSánchez-Rovira, Pedro
dc.contributor.authorRamos Vázquez, Manuel
dc.contributor.authorGarcia-Sáenz, José Ángel
dc.contributor.authorAntón, Antonio
dc.contributor.authorMuñoz, Montserrat
dc.contributor.authorde Juan, Ana
dc.contributor.authorJara, Carlos
dc.contributor.authorChacón, José Ignacio
dc.contributor.authorArcusa, Angels
dc.contributor.authorGil-Gil, Miguel
dc.contributor.authorAdrover, Encarna
dc.contributor.authorOltra, Amparo
dc.contributor.authorBrunet, Joan
dc.contributor.authorGonzález, Sonia
dc.contributor.authorBezares, Susana
dc.contributor.authorLope, Virginia 
dc.contributor.authorMartín, Miguel
dc.contributor.authorPollan-Santamaria, Marina 
dc.date.accessioned2020-08-26T07:51:59Z
dc.date.available2020-08-26T07:51:59Z
dc.date.issued2020-05-08
dc.identifier.citationSci Rep. 2020; 10: 7741.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/10903
dc.description.abstractThis study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and residence- matched controls were included. Clinical, epidemiological, HRQL (SF-36) and PD information (GHQ-28) was collected. We used multivariable logistic regression models to estimate OR of low HRQL and of PD in cases compared to controls, and to identify factors associated with low HRQL and with PD. Among 896 BC cases and 890 control women, cases had poorer scores than both, the reference population and the control group, in all SF-36 scales. BC women with lower education, younger, active workers, never smokers, those with comorbidities, in stage IV and with surgical treatment had lower physical HRQL; factors associated with low mental HRQL were dissatisfaction with social support, being current smoker and having children. Cases had a fivefold increased odds of PD compared to controls. Managing comorbidities and trying to promote social support, especially in younger and less educated women, could improve well-being of BC patients.es_ES
dc.description.sponsorshipThis study was supported by Fundación Científica Asociación Española Contra el Cáncer (AECC) (Scientific Foundation of the Spanish Association Against Cancer), Fundación Cerveza y Salud 2005 (Beer and Health Foundation 2005), Sociedad Española de Oncología Médica (SEOM) (Spanish Society of Medical Oncology), Ministerio de Economía y Competitividad (Spanish Ministry of Economy and Competitiveness, IJCI-2014–20900), and Federación Española de Cáncer de Mama (FECMA) (Spanish Federation of Breast Cancer). The funding bodies did not have any role in the design of the study, in the collection, analysis, and interpretation of data or in writing the manuscript.es_ES
dc.language.isoenges_ES
dc.publisherNature Researches_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectQuality of lifees_ES
dc.subjectEpidemiologyes_ES
dc.subjectBreast canceres_ES
dc.subjectCancer epidemiologyes_ES
dc.titlePrimary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study.es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID32385335es_ES
dc.format.volume10es_ES
dc.format.number1es_ES
dc.format.page7741es_ES
dc.identifier.doi10.1038/s41598-020-63637-wes_ES
dc.contributor.funderFederación Española de Cáncer de Mama
dc.contributor.funderAsociación Española Contra el Cáncer
dc.contributor.funderSociedad Española de Oncología Médica
dc.contributor.funderMinisterio de Economía y Competitividad (España)
dc.description.peerreviewedes_ES
dc.identifier.e-issn2045-2322es_ES
dc.relation.publisherversionhttps://dx.doi.org/10.1038%2Fs41598-020-63637-wes_ES
dc.identifier.journalScientific reportses_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/IJCI-2014–20900es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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