Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/10903
Título
Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study.
Autor(es)
Fernandez de Larrea-Baz, Nerea ISCIII | Perez-Gomez, Beatriz ISCIII | Guerrero-Zotano, Ángel | Casas, Ana María | Bermejo, Begoña | Baena-Cañada, José Manuel | Antolín, Silvia | Sánchez-Rovira, Pedro | Ramos Vázquez, Manuel | Garcia-Sáenz, José Ángel | Antón, Antonio | Muñoz, Montserrat | de Juan, Ana | Jara, Carlos | Chacón, José Ignacio | Arcusa, Angels | Gil-Gil, Miguel | Adrover, Encarna | Oltra, Amparo | Brunet, Joan | González, Sonia | Bezares, Susana | Lope Carvajal, Virginia ISCIII | Martín, Miguel | Pollan-Santamaria, Marina ISCIII
Fecha de publicación
2020-05-08
Cita
Sci Rep. 2020; 10: 7741.
Idioma
Inglés
Tipo de documento
journal article
Resumen
This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and residence- matched controls were included. Clinical, epidemiological, HRQL (SF-36) and PD information (GHQ-28) was collected. We used multivariable logistic regression models to estimate OR of low HRQL and of PD in cases compared to controls, and to identify factors associated with low HRQL and with PD. Among 896 BC cases and 890 control women, cases had poorer scores than both, the reference population and the control group, in all SF-36 scales. BC women with lower education, younger, active workers, never smokers, those with comorbidities, in stage IV and with surgical treatment had lower physical HRQL; factors associated with low mental HRQL were dissatisfaction with social support, being current smoker and having children. Cases had a fivefold increased odds of PD compared to controls. Managing comorbidities and trying to promote social support, especially in younger and less educated women, could improve well-being of BC patients.
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DOI
Aparece en las colecciones
- Investigación > IIS > INCLIVA - Instituto de Investigación Sanitaria Fundación para la Investigación del Hospital Clínico de Valencia (C. Valenciana)
- Investigación > IIS > IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
- Investigación > ISCIII > Centro Nacional de Epidemiología (CNE)
- Investigación > IIS > IiSGM - Instituto de Investigación Sanitaria Gregorio Marañón (Madrid)