Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/10879
Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women
del Pozo, María del Pilar | Criado-Navarro, Inmaculada | Romieu, Isabelle | Chajès, Véronique | Priego-Capote, Feliciano | Pollan-Santamaria, Marina ISCIII | Perez-Gomez, Beatriz ISCIII | Sierra, Maria Angeles ISCIII | de Lucas, Maria Pilar ISCIII | Castello Pastor, Adela ISCIII | Ruiz Moreno, Emma ISCIII | Fernandez de Larrea-Baz, Nerea ISCIII | Pastor-Barriuso, Roberto ISCIII | Lope Carvajal, Virginia ISCIII
Nutrients . 2020 Jun 25;12(6):1895.
This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography-mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids.
Files in this item
- SerumPhospholipidFattyAcids_20 ...