Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/10093
Título
Perfluorinated alkyl substances in Spanish adults: Geographical distribution and determinants of exposure
Autor(es)
Bartolome, Monica ISCIII | Gallego-Picó, Alejandrina | Cutanda, Francisco | Huetos, Olga ISCIII | Esteban-Lopez, Marta ISCIII | Perez-Gomez, Beatriz ISCIII | Castaño, Argelia ISCIII
Fecha de publicación
2017-12-15
Cita
Sci Total Environ. 2017 Dec 15;603-604:352-360.
Idioma
Inglés
Tipo de documento
journal article
Resumen
Per- and polyfluoroalkyl substances (PFAS) are widely found in humans and the environment. Their persistence, bioaccumulation and toxicity make them a source of increasing public health concern. In this study, we analyzed the concentrations and geographical distribution of six PFAS in the serum of 755 Spanish adults aged 18-65. The geometric mean concentrations (and P95 values) for PFOS (perfluoroctane sulfonate), PFOA (perfluorooctanoic acid), PFHxS (perfluorohexane sulfonate), PFNA (perfluorononanoic acid) and PFDA (perfluorodecanoic acid) were 7.67 (19.3), 1.99 (5.48), 0.91 (2.84), 0.96 (2.44) and 0.42 (0.99) μg/L, respectively. N-Methylperfluorooctane sulfonamide (N-MeFOSAA) was detected in only 3.3% of samples. Residents in northeast (Catalonia) and northwest of Spain (Galicia) were found to have the highest serum values, whereas residents in the Canary Islands had the lowest values for almost all PFAS. Men presented higher levels than women, and we confirm that lactation (breastfeeding) contributes to a reduced body burden for all PFAS in women. Our data provide new information on exposure to PFAS in a national cross section sample of Spanish adults, thus providing a proxy for reference values for the Spanish population and forming the base for following temporal trends in the future.
Palabras clave
Exposure Spanish adults | Human biomonitoring | Human serum samples | PFOA | PFOS | Perfluorinated alkyl substances
MESH
Adolescent | Adult | Alkanesulfonates | Environmental Exposure | Environmental Pollutants | Female | Fluorocarbons | Humans | Lactation | Male | Middle Aged | Spain | Young Adult
Versión en línea
DOI
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