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dc.contributor.authorvan den Berg, Maayken Elizabeth Louise
dc.contributor.authorCastellote, Juan Manuel 
dc.contributor.authorMayordomo, Jose Ignacio
dc.contributor.authorMahillo-Fernandez, Ignacio 
dc.contributor.authorPedro-Cuesta, Jesus de
dc.identifier.citationBiomed Res Int. 2017;2017:2478197.es_ES
dc.description.abstractPURPOSE: Understanding the presentation of spinal cord injury (SCI) due to tumours considering population distribution and temporal trends is key to managing SCI health services. This study quantified incidence rates, function scores, and trends of SCI due to tumour or metastasis over an 18-year time period in a defined region in Spain. METHODS: A retrospective cohort study included in-and outpatients with nontraumatic SCI due to tumour or metastasis admitted to a metropolitan hospital in Spain between 1991 and 2008. Main outcome measures were crude and age- and sex-adjusted incidence rates, tumour location and type, distribution by spinal level, neurological level of injury, and impairment ASIA scores. RESULTS: Primary tumour or metastasis accounted for 32.5% of nontraumatic SCI with an incidence rate of 4.1 per million population. Increasing rates with age and over time were observed. Major pathology groups were intradural-extramedullary masses from which meningiomas and neurinomas accounted for 40%. Lesions were mostly incomplete with predominant ASIA Grade D. CONCLUSIONS: Increasing incidence rates of tumour-related SCI over time in the middle-aged and the elderly suggest a growing need for neurooncology health resources in the future.es_ES
dc.description.sponsorshipThis study was supported by the Ministry of Education (Grant SB2009-0175 to Maayken Elizabeth Louise van den Berg) and the Carlos III Institute of Health (Grants TPY 1529/07, TPY 1444/08, and ESPY 1281/15 to Juan M. Castellote). The authors would like to thank the staff of the Servet Hospital and especially the medical staff of the SCI unit at the Rehabilitation Service that facilitated access to information.es_ES
dc.publisherHindawi es_ES
dc.subject.meshAge Factors es_ES
dc.subject.meshAged es_ES
dc.subject.meshAged, 80 and over es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshNeoplasms es_ES
dc.subject.meshSpain es_ES
dc.subject.meshSpinal Cord Injuries es_ES
dc.subject.meshTrauma Centers es_ES
dc.titleSpinal Cord Injury due to Tumour or Metastasis in Aragón, Northeastern Spain (1991-2008): Incidence, Time Trends, and Neurological Functiones_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III 
dc.identifier.journalBioMed research internationales_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/TPY 1529/07es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/TPY 1444/08es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/ESPY 1281/15es_ES
dc.rights.accessRightsopen accesses_ES

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Atribución 4.0 Internacional
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