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dc.contributor.authorKrone, Manuel
dc.contributor.authorGray, Steve
dc.contributor.authorAbad, Raquel 
dc.contributor.authorSkoczyńska, Anna
dc.contributor.authorStefanelli, Paola
dc.contributor.authorvan der Ende, Arie
dc.contributor.authorTzanakaki, Georgina
dc.contributor.authorMölling, Paula
dc.contributor.authorJoão Simões, Maria
dc.contributor.authorKřížová, Pavla
dc.contributor.authorEmonet, Stéphane
dc.contributor.authorCaugant, Dominique A
dc.contributor.authorToropainen, Maija
dc.contributor.authorDopazo, Ana 
dc.contributor.authorWaśko, Izabela
dc.contributor.authorKnol, Mirjam J
dc.contributor.authorJacobsson, Susanne
dc.contributor.authorRodrigues Bettencourt, Célia
dc.contributor.authorMusilek, Martin
dc.contributor.authorBorn, Rita
dc.contributor.authorVogel, Ulrich
dc.contributor.authorBorrow, Ray
dc.date.accessioned2020-01-29T11:49:53Z
dc.date.available2020-01-29T11:49:53Z
dc.date.issued2019-04
dc.identifier.citationEuro Surveill. 2019 Apr;24(14).es_ES
dc.identifier.issn1560-7917es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8979
dc.description.abstractBackgroundThe total incidence of invasive meningococcal disease (IMD) in Europe has been declining in recent years; however, a rising incidence due to serogroup W (MenW), predominantly sequence type 11 (ST-11), clonal complex 11 (cc11), was reported in some European countries.AimThe aim of this study was to compile the most recent laboratory surveillance data on MenW IMD from several European countries to assess recent trends in Europe.MethodsIn this observational, retrospective study, IMD surveillance data collected from 2013-17 by national reference laboratories and surveillance units from 13 European countries were analysed using descriptive statistics.ResultsThe overall incidence of IMD has been stable during the study period. Incidence of MenW IMD per 100,000 population (2013: 0.03; 2014: 0.05; 2015: 0.08; 2016: 0.11; 2017: 0.11) and the proportion of this serogroup among all invasive cases (2013: 5% (116/2,216); 2014: 9% (161/1,761); 2015: 13% (271/2,074); 2016: 17% (388/2,222); 2017: 19% (393/2,112)) continuously increased. The most affected countries were England, the Netherlands, Switzerland and Sweden. MenW was more frequent in older age groups (≥ 45 years), while the proportion in children (< 15 years) was lower than in other age groups. Of the culture-confirmed MenW IMD cases, 80% (615/767) were caused by hypervirulent cc11.ConclusionDuring the years 2013-17, an increase in MenW IMD, mainly caused by MenW cc11, was observed in the majority of European countries. Given the unpredictable nature of meningococcal spread and the epidemiological potential of cc11, European countries may consider preventive strategies adapted to their contexts.es_ES
dc.description.sponsorshipThis publication made use of the PubMLST website (https://pubmlst.org/) developed by Keith Jolley (Jolley & Maiden 2010, BMC Bioinformatics, 11:595) and the MRF Meningococcus Genome Library (https://www.meningitis.org/research-projects/mrf-meningococcus-genome-library). The development was funded by the Wellcome Trust.es_ES
dc.language.isoenges_ES
dc.publisherEuropean Centre for Disease Prevention and Controles_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectEuropees_ES
dc.subjectNeisseria menigitidises_ES
dc.subjectairborne infectionses_ES
dc.subjectbacterial infectionses_ES
dc.subjectepidemiologyes_ES
dc.subjectmeningococcal diseasees_ES
dc.subjectserogroup Wes_ES
dc.subjectsurveillancees_ES
dc.titleIncrease of invasive meningococcal serogroup W disease in Europe, 2013 to 2017es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID30968827es_ES
dc.format.volume24es_ES
dc.format.number14es_ES
dc.identifier.doi10.2807/1560-7917.ES.2019.24.14.1800245es_ES
dc.contributor.funderWellcome Trustes_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1560-7917es_ES
dc.relation.publisherversionhttps://doi.org/10.2807/1560-7917.ES.2019.24.14.1800245es_ES
dc.identifier.journalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletines_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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