Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/8793
First detection of Aspergillus fumigatus azole-resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain
New Microbes New Infect. 2015 Apr 20;6:33-4. doi: 10.1016/j.nmni.2015.04.005. eCollection 2015 Jul.
We report the first isolation of a voriconazole-resistant Aspergillus fumigatus strain harbouring the azole resistance mechanism TR46/Y121F/T289A, recovered from an azole-naive patient in Spain with chronic obstructive pulmonary disease. This new finding in Spain suggests the spread of this resistance mechanism and reinforces the need for antifungal susceptibility surveillance.