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dc.contributor.authorCatala-Lopez, Ferran 
dc.contributor.authorRidao, Manuel
dc.contributor.authorNúñez-Beltrán, Amparo
dc.contributor.authorGènova-Maleras, Ricard
dc.contributor.authorAlonso-Arroyo, Adolfo
dc.contributor.authorAleixandre-Benavent, Rafael
dc.contributor.authorCatalá, Miguel A
dc.contributor.authorTabarés-Seisdedos, Rafael
dc.date.accessioned2019-04-12T06:52:02Z
dc.date.available2019-04-12T06:52:02Z
dc.date.issued2019-02-11
dc.identifier.citationSyst Rev. 2019 Feb 11;8(1):49.es_ES
dc.identifier.issn2046-4053es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7453
dc.description.abstractBACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder characterized by a persistent pattern of symptoms of developmentally inappropriate and impaired inattention and/or hyperactivity/impulsivity, with difficulties often continuing into adulthood. ADHD can come with other comorbid conditions. The aim of this study will be to quantify the prevalence and comorbidity of ADHD among children, adolescent, and adult population in Spain. METHODS/DESIGN: We designed and registered a study protocol for an update and expansion of a systematic review and meta-analysis of pooled prevalence data. We will include cross-sectional observational studies reporting prevalence of ADHD in Spain and conducted in the general population, outpatient, and/or school settings. The primary outcome will be the prevalence of ADHD. Secondary outcomes will be the prevalence of any physical or mental comorbidity in association with ADHD. No limitations will be imposed on publication status, study conduct period, and language of dissemination. Comprehensive literature searches will be conducted in multiple electronic databases, including PubMed/MEDLINE, EMBASE, Scopus, Web of Science, PsycINFO, IME - Spanish Medical Index, and IBECS - Spanish Bibliographic Index of Health Sciences. We will also search Google Scholar, dissertation databases, and conference abstracts. Two team members will independently screen all citations, full-text articles, and abstract data. Potential conflicts will be resolved through discussion. The methodological quality (or risk of bias) of individual studies will be appraised using an appropriate tool. If feasible, we will conduct random effects meta-analysis. Prevalence estimates will be stratified according to gender, age, and geographical location. Additional analyses will be conducted to explore the potential sources of heterogeneity (e.g., methodological quality, sample size, diagnostic criteria). DISCUSSION: This systematic review and meta-analysis of observational data will provide an updated synthesis of the prevalence and comorbidity of ADHD in Spain. This study will also examine factors that may explain potential variations in prevalence data. The findings of this study will be published in a peer-reviewed journal. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42018106082 .es_ES
dc.description.sponsorshipFC-L and RT-S are funded by CIBERSAM/Institute of Health Carlos III. MR is partially funded by the Spanish Health Services Research on Chronic Patients Network (REDISSEC)/Institute of Health Carlos III. The funders were not involved in the design of the protocol or decision to submit the protocol for publication, nor will they be involved in any aspect of the conduct of the study.es_ES
dc.language.isoenges_ES
dc.publisherBioMed Central (BMC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAttention deficit hyperactivity disorderes_ES
dc.subjectComorbidityes_ES
dc.subjectEpidemiological studyes_ES
dc.subjectMeta-analysises_ES
dc.subjectPrevalencees_ES
dc.subjectSpaines_ES
dc.subjectSystematic reviewes_ES
dc.titlePrevalence and comorbidity of attention deficit hyperactivity disorder in Spain: study protocol for extending a systematic review with updated meta-analysis of observational studieses_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID30744675es_ES
dc.format.volume8es_ES
dc.format.number1es_ES
dc.format.page49es_ES
dc.identifier.doi10.1186/s13643-019-0967-yes_ES
dc.contributor.funderInstituto de Salud Carlos III 
dc.description.peerreviewedes_ES
dc.identifier.e-issn2046-4053es_ES
dc.relation.publisherversionhttps://doi.org/10.1186/s13643-019-0967-yes_ES
dc.identifier.journalSystematic reviewses_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional