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dc.contributor.authorRábano, Alberto
dc.contributor.authorPedro-Cuesta, Jesus de 
dc.contributor.authorMølbak, Kåre
dc.contributor.authorSiden, Ake
dc.contributor.authorCalero, Miguel 
dc.contributor.authorLaursen, Henning
dc.date.accessioned2019-02-04T09:49:54Z
dc.date.available2019-02-04T09:49:54Z
dc.date.issued2005-01-24
dc.identifier.citationBMC Public Health. 2005 Jan 24;5:9.es_ES
dc.identifier.issn1471-2458es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7078
dc.description.abstractBACKGROUND: Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results. METHODS: Within the context of a case-control study designed to address surgical risk of sporadic Creutzfeldt-Jakob Disease in Nordic European countries (EUROSURGYCJD Project), a strategy was adopted to categorise reported surgical procedures in terms of potential risk of Creutzfeldt-Jakob Disease acquisition. We took into account elements of biological plausibility, either clinically or experimentally demonstrated, such as tissue infectivity, PrP expression content or successful route of infection. RESULTS: We propose a classification of exposed tissues and anatomic structures, drawn up on the basis of their specific putative role as entry site for prion transmission through contact with surgical instruments that are not fully decontaminated. CONCLUSIONS: This classification can serve as a reference, both in our study and in further epidemiological research, for categorisation of surgical procedures in terms of risk level of Creutzfeldt-Jakob Disease acquisition.es_ES
dc.language.isoenges_ES
dc.publisherBiomed Centrales_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshCase-Control Studies es_ES
dc.subject.meshCreutzfeldt-Jakob Syndrome es_ES
dc.subject.meshCross Infection es_ES
dc.subject.meshDenmark es_ES
dc.subject.meshFinland es_ES
dc.subject.meshHumans es_ES
dc.subject.meshPrPSc Proteins es_ES
dc.subject.meshRegistries es_ES
dc.subject.meshRisk Assessment es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSterilization es_ES
dc.subject.meshSurgical Instruments es_ES
dc.subject.meshSurgical Procedures, Operativees_ES
dc.subject.meshSweden es_ES
dc.subject.meshTissue Culture Techniques es_ES
dc.subject.meshEquipment Contamination es_ES
dc.titleTissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levelses_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID15667663es_ES
dc.format.volume5es_ES
dc.format.number1es_ES
dc.format.page9es_ES
dc.identifier.doi10.1186/1471-2458-5-9es_ES
dc.description.peerreviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1186/1471-2458-5-9es_ES
dc.identifier.journalBMC public healthes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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