Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/6592
Título
Human Papillomavirus (HPV) Genotyping: Automation and Application in Routine Laboratory Testing
Autor(es)
Fraile, Lorenzo ISCIII | Echevarria, Jose Manuel ISCIII | Hernandez Novoa, B | Ortiz Rivera, Marta ISCIII | Torres, Montserrat ISCIII
Fecha de publicación
2012
Cita
Open Virol J. 2012;6:144-50.
Idioma
Inglés
Tipo de documento
journal article
Resumen
A large number of assays designed for genotyping human papillomaviruses (HPV) have been developed in the last years. They perform within a wide range of analytical sensitivity and specificity values for the different viral types, and are used either for diagnosis, epidemiological studies, evaluation of vaccines and implementing and monitoring of vaccination programs. Methods for specific genotyping of HPV-16 and HPV-18 are also useful for the prevention of cervical cancer in screening programs. Some commercial tests are, in addition, fully or partially automated. Automation of HPV genotyping presents advantages such as the simplicity of the testing procedure for the operator, the ability to process a large number of samples in a short time, and the reduction of human errors from manual operations, allowing a better quality assurance and a reduction of cost. The present review collects information about the current HPV genotyping tests, with special attention to practical aspects influencing their use in clinical laboratories.
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