dc.contributor.author | Garcia-Arellano, Ana | |
dc.contributor.author | Ramallal, Raul | |
dc.contributor.author | Ruiz-Canela, Miguel | |
dc.contributor.author | Salas-Salvado, Jordi | |
dc.contributor.author | Corella, Dolores | |
dc.contributor.author | Shivappa, Nitin | |
dc.contributor.author | Schroeder, Helmut | |
dc.contributor.author | Hebert, James R | |
dc.contributor.author | Ros, Emilio | |
dc.contributor.author | Gomez-Garcia, Enrique | |
dc.contributor.author | Estruch, Ramon | |
dc.contributor.author | Lapetra, Jose | |
dc.contributor.author | Aros, Fernando | |
dc.contributor.author | Fiol Sala, Miquel | |
dc.contributor.author | Serra-Majem, Lluis | |
dc.contributor.author | Pinto, Xavier | |
dc.contributor.author | Babio, Nancy | |
dc.contributor.author | Gonzalez, Jose I | |
dc.contributor.author | Fito, Montserrat | |
dc.contributor.author | Alfredo Martinez, J | |
dc.contributor.author | Martinez-Gonzalez, Miguel A | |
dc.contributor.author | PREDIMED Investigators | |
dc.date.accessioned | 2024-07-04T12:55:03Z | |
dc.date.available | 2024-07-04T12:55:03Z | |
dc.date.issued | 2015-06 | |
dc.identifier.citation | Garcia-Arellano A, Ramallal R, Ruiz-Canela M, Salas-Salvado J, Corella D, Shivappa N, et al. Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study. Nutrients. 2015 Jun;7(6):4124-38. | en |
dc.identifier.other | http://hdl.handle.net/20.500.13003/10832 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20122 | |
dc.description.abstract | Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the context of a dietary pattern. We prospectively examined the association between the DII and the incidence of cardiovascular disease (CVD: myocardial infarction, stroke or cardiovascular death) in the PREDIMED (Prevencion con Dieta Mediterranea) study including 7216 high-risk participants. The DII was computed based on a validated 137-item food frequency questionnaire. Multivariate-adjusted hazard ratios (HR) and 95% confidence intervals of CVD risk were computed across quartiles of the DII where the lowest (most anti-inflammatory) quartile is the referent. Risk increased across the quartiles (i.e., with increasing inflammatory potential): HRquartile2 = 1.42 (95%CI = 0.97-2.09); HRquartile3 = 1.85 (1.27-2.71); and HRquartile4 = 1.73 (1.15-2.60). When fit as continuous the multiple-adjusted hazard ratio for each additional standard deviation of the DII was 1.22 (1.06-1.40). Our results provide direct prospective evidence that a pro-inflammatory diet is associated with a higher risk of cardiovascular clinical events. | en |
dc.description.sponsorship | This research was supported by the official funding agency for biomedical research of the Spanish government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, to RE; RTIC RD 06/0045, to MAM-G) and through Centro de Investigacion Biomedica en Red de Fisiopatologia de la Obesidad y Nutricion (CIBERobn), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), the Fondo de Investigacion Sanitaria-Fondo Europeo de Desarrollo Regional (Proyecto de Investigacion (PI) 04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, P11/02505 and PI13/00462), the Ministerio de Ciencia e Innovacion (Recursos y teconologia agroalimentarias (AGL)-2009-13906-C02 and AGL2010-22319-C03 and AGL2013-49083-C3-1-R), the Fundacion Mapfre 2010, the Consejeria de Salud de la Junta de Andalucia (PI0105/2007), the Public Health Division of the Department of Health of the Autonomous Government of Catalonia, the Generalitat Valenciana (Generalitat Valenciana Ayuda Complementatia (GVACOMP) 06109, GVACOMP2010-181, GVACOMP2011-151), Conselleria de Sanitat y AP; Atencion Primaria (CS) 2010-AP-111, and CS2011-AP-042), Regional Government of Navarra (P27/2011), and Centre Catala de la Nutricio de l'Institut d'Estudis Catalans. ET is supported by a Rio Hortega post-residency fellow of the Instituto de Salud Carlos III, Ministry of Economy and Competitiveness, Spanish Government. | es_ES |
dc.language.iso | eng | en |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Dietary inflammatory index | en |
dc.subject | Cardiovascular disease | en |
dc.subject | PREDIMED | en |
dc.subject | Inflammation | en |
dc.subject.mesh | Cardiovascular Diseases | * |
dc.subject.mesh | Aged, 80 and over | * |
dc.subject.mesh | Aged | * |
dc.subject.mesh | Energy Intake | * |
dc.subject.mesh | Follow-Up Studies | * |
dc.subject.mesh | Humans | * |
dc.subject.mesh | Inflammation | * |
dc.subject.mesh | Middle Aged | * |
dc.subject.mesh | Nuts | * |
dc.subject.mesh | Male | * |
dc.subject.mesh | Multivariate Analysis | * |
dc.subject.mesh | Prospective Studies | * |
dc.subject.mesh | Female | * |
dc.subject.mesh | Endpoint Determination | * |
dc.subject.mesh | Risk Factors | * |
dc.subject.mesh | Proportional Hazards Models | * |
dc.subject.mesh | Treatment Outcome | * |
dc.subject.mesh | Body Mass Index | * |
dc.subject.mesh | Diet, Mediterranean | * |
dc.subject.mesh | Olive Oil | * |
dc.subject.mesh | Surveys and Questionnaires | * |
dc.subject.mesh | Incidence | * |
dc.title | Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study | en |
dc.type | research article | en |
dc.rights.license | Attribution 4.0 International | * |
dc.identifier.pubmedID | 26035241 | es_ES |
dc.format.volume | 7 | es_ES |
dc.format.number | 6 | es_ES |
dc.format.page | 4124-4138 | es_ES |
dc.identifier.doi | 10.3390/nu7064124 | |
dc.identifier.e-issn | 2072-6643 | es_ES |
dc.relation.publisherversion | https://dx.doi.org/10.3390/nu7064124 | en |
dc.identifier.journal | Nutrients | es_ES |
dc.rights.accessRights | open access | en |
dc.subject.decs | Índice de Masa Corporal | * |
dc.subject.decs | Dieta Mediterránea | * |
dc.subject.decs | Incidencia | * |
dc.subject.decs | Modelos de Riesgos Proporcionales | * |
dc.subject.decs | Resultado del Tratamiento | * |
dc.subject.decs | Femenino | * |
dc.subject.decs | Análisis Multivariante | * |
dc.subject.decs | Aceite de Oliva | * |
dc.subject.decs | Masculino | * |
dc.subject.decs | Determinación de Punto Final | * |
dc.subject.decs | Estudios de Seguimiento | * |
dc.subject.decs | Factores de Riesgo | * |
dc.subject.decs | Humanos | * |
dc.subject.decs | Persona de Mediana Edad | * |
dc.subject.decs | Nueces | * |
dc.subject.decs | Ingestión de Energía | * |
dc.subject.decs | Estudios Prospectivos | * |
dc.subject.decs | Inflamación | * |
dc.subject.decs | Anciano | * |
dc.subject.decs | Anciano de 80 o más Años | * |
dc.subject.decs | Encuestas y Cuestionarios | * |
dc.subject.decs | Enfermedades Cardiovasculares | * |
dc.identifier.scopus | 2-s2.0-85018224708 | |
dc.identifier.wos | 357281800010 | |
dc.identifier.pui | L604764910 | |