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dc.contributor.author | Pascual, Sergi | |
dc.contributor.author | Feimer, Jan | |
dc.contributor.author | De Soyza, Anthony | |
dc.contributor.author | Roig, Jaume Sauleda | |
dc.contributor.author | Haughney, John | |
dc.contributor.author | Padulles, Laura | |
dc.contributor.author | Seoane, Beatriz | |
dc.contributor.author | Rekeda, Ludmyla | |
dc.contributor.author | Ribera, Anna | |
dc.contributor.author | Chrystyn, Henry | |
dc.date.accessioned | 2024-07-04T12:54:59Z | |
dc.date.available | 2024-07-04T12:54:59Z | |
dc.date.issued | 2015-04-30 | |
dc.identifier.citation | Pascual S, Feimer J, De Soyza A, Sauleda Roig J, Haughney J, Padulles L, et al. Preference, satisfaction and critical errors with Genuair and Breezhaler inhalers in patients with COPD: a randomised, cross-over, multicentre study. NPJ Prim Care Respir Med. 2015 Apr 30;25:15018. | en |
dc.identifier.issn | 2055-1010 | |
dc.identifier.other | http://hdl.handle.net/20.500.13003/10874 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20114 | |
dc.description.abstract | BACKGROUND: The specific attributes of inhaler devices can influence patient use, satisfaction and treatment compliance, and may ultimately impact on clinical outcomes in patients with chronic obstructive pulmonary disease (COPD). AIMS: To assess patient preference, satisfaction and critical inhaler technique errors with Genuair (a multidose inhaler) and Breezhaler (a single-dose inhaler) after 2 weeks of daily use. METHODS: Patients with COPD and moderate to severe airflow obstruction were randomised in a cross-over, open-label, multicentre study to consecutive once-daily inhalations of placebo via Genuair and Breezhaler, in addition to current COPD medication. The primary end point was the proportion of patients who preferred Genuair versus Breezhaler after 2 weeks (Patient Satisfaction and Preference Questionnaire). Other end points included overall satisfaction and correct use of the inhalers after 2 weeks, and willingness to continue with each device. RESULTS: Of the 128 patients enrolled, 127 were included in the safety population (male n = 91; mean age 67.6 years). Of the 110 of the 123 patients in the intent-to-treat population who indicated an inhaler preference, statistically significantly more patients preferred Genuair than Breezhaler (72.7 vs. 27.3%; P < 0.001). Mean overall satisfaction scores were also greater for Genuair than for Breezhaler (5.9 vs. 5.3, respectively; P < 0.001). After 2 weeks, there was no statistically significant difference in the number of patients who made >= 1 critical inhaler technique error with Breezhaler than with Genuair (7.3 vs. 3.3%, respectively). CONCLUSIONS: Patient overall preference and satisfaction was significantly higher with Genuair compared with Breezhaler. The proportion of patients making critical inhaler technique errors was low with Genuair and Breezhaler. | en |
dc.description.sponsorship | The study was funded by Almirall S.A., Barcelona, Spain, and Forest Laboratories LLC, a subsidiary of Actavis PLC, New York, USA. Medical writing support was funded by Almirall S.A., Barcelona, Spain. | es_ES |
dc.language.iso | eng | en |
dc.publisher | Nature Publishing Group | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | Aged | * |
dc.subject.mesh | Male | * |
dc.subject.mesh | Equipment Design | * |
dc.subject.mesh | Nebulizers and Vaporizers | * |
dc.subject.mesh | Patient Satisfaction | * |
dc.subject.mesh | Cross-Over Studies | * |
dc.subject.mesh | Female | * |
dc.subject.mesh | Equipment Failure | * |
dc.subject.mesh | Respiratory System Agents | * |
dc.subject.mesh | Pulmonary Disease, Chronic Obstructive | * |
dc.subject.mesh | Humans | * |
dc.subject.mesh | Middle Aged | * |
dc.title | Preference, satisfaction and critical errors with Genuair and Breezhaler inhalers in patients with COPD: a randomised, cross-over, multicentre study | en |
dc.type | research article | en |
dc.rights.license | Attribution 4.0 International | * |
dc.identifier.pubmedID | 25927321 | es_ES |
dc.format.volume | 25 | es_ES |
dc.format.page | 15018 | es_ES |
dc.identifier.doi | 10.1038/npjpcrm.2015.18 | |
dc.relation.publisherversion | https://dx.doi.org/10.1038/npjpcrm.2015.18 | en |
dc.identifier.journal | NPJ Primary Care Respiratory Medicine | es_ES |
dc.rights.accessRights | open access | en |
dc.subject.decs | Enfermedad Pulmonar Obstructiva Crónica | * |
dc.subject.decs | Humanos | * |
dc.subject.decs | Persona de Mediana Edad | * |
dc.subject.decs | Satisfacción del Paciente | * |
dc.subject.decs | Anciano | * |
dc.subject.decs | Estudios Cruzados | * |
dc.subject.decs | Femenino | * |
dc.subject.decs | Diseño de Equipo | * |
dc.subject.decs | Fármacos del Sistema Respiratorio | * |
dc.subject.decs | Falla de Equipo | * |
dc.subject.decs | Masculino | * |
dc.subject.decs | Nebulizadores y Vaporizadores | * |
dc.identifier.scopus | 2-s2.0-84933535700 | |
dc.identifier.wos | 354189900001 | |
dc.identifier.pui | L605195736 |
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