dc.contributor.author | Burguera, Bartolome | |
dc.contributor.author | Tur, Juan Jesus | |
dc.contributor.author | Escudero, Antonio Jorge | |
dc.contributor.author | Alos, Maria | |
dc.contributor.author | Pagan, Alberto | |
dc.contributor.author | Cortes, Baltasar | |
dc.contributor.author | González-Argenté, Francesc Xavier | |
dc.contributor.author | Soriano, Joan B. | |
dc.date.accessioned | 2024-07-04T12:54:48Z | |
dc.date.available | 2024-07-04T12:54:48Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Burguera B, Tur Juan J, Escudero AJ, Alos M, Pagan A, Cortes Miro B, et al. An Intensive Lifestyle Intervention Is an Effective Treatment of Morbid Obesity: The TRAMOMTANA Study-A Two-Year Randomized Controlled Clinical Trial. Int J Endocrinol. 2015;2015:194696. Epub 2015 Jul 15. | en |
dc.identifier.issn | 1687-8337 | |
dc.identifier.other | http://hdl.handle.net/20.500.13003/11021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20087 | |
dc.description.abstract | Bariatric surgery is currently the most effective therapy to induce weight loss in morbidly obese patients. Objective. This controlled, clinical trial with a two-year intervention was aimed at comparing the efficacy of two nonsurgical approaches versus bariatric surgery, on body weight changes and metabolic parameters in morbidly obese patients. Methods. Patients were randomized to an Intensive Lifestyle Intervention (ILI) (n - 60) or Conventional Obesity Therapy ( COT) (n - 46). The ILI group received behavioral therapy and nutritional counseling. The COT group received standard medical treatment. They were compared with a third group, Surgical Obesity Group ( SOG) (n = 37). Results. Patients who received ILI had a greater percentage of weight loss than patients receiving COT (-11.3% versus -1.6%; P < 0.0044). Interestingly 31.4% of patients included in the ILI group were no longer morbidly obese after just six months of intervention, increasing to 44.4% after 24 months of intervention. The percentage weight loss in SOG was -29.6% after that same period of time. Conclusions. ILI was associated with significant weight loss when compared to COT, in a group of patients with obesity. An ILI approach could be an alternative therapy to patients with obesity, who are not candidates to undergo bariatric surgery. | en |
dc.description.sponsorship | The authors thank the staff of the Hospital Universitario Son Espases Biobank (code RD09/076/054) and Son Espases Research Unit, for the assistance in laboratory measurements, data handling, processing, and storage of the biological samples. They thank all participants in this clinical trial. TRAMOMTANA was funded by a project grant from the Mutua Madrilena Medical Foundation and the Instituto de Salud Carlos III (ISCiii) (FIS: PI071250) and Spanish Clinical Research Network (CAIBER) which had no influence over the trial's conduct. | es_ES |
dc.language.iso | eng | en |
dc.publisher | Hindawi | en |
dc.rights.uri | https://creativecommons.org/licenses/by/3.0/ | * |
dc.title | An Intensive Lifestyle Intervention Is an Effective Treatment of Morbid Obesity: The TRAMOMTANA Study-A Two-Year Randomized Controlled Clinical Trial | en |
dc.type | research article | en |
dc.rights.license | Attribution 3.0 Unported | * |
dc.identifier.pubmedID | 26257780 | es_ES |
dc.format.volume | 2015 | es_ES |
dc.format.page | 194696 | es_ES |
dc.identifier.doi | 10.1155/2015/194696 | |
dc.identifier.e-issn | 1687-8345 | es_ES |
dc.relation.publisherversion | https://dx.doi.org/10.1155/2015/194696 | en |
dc.identifier.journal | International Journal of Endocrinology | es_ES |
dc.rights.accessRights | open access | en |
dc.identifier.scopus | 2-s2.0-84938150106 | |
dc.identifier.wos | 358494400001 | |
dc.identifier.pui | L605340897 | |