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dc.contributor.author | Mejia-Lancheros, Cilia | |
dc.contributor.author | Estruch, Ramon | |
dc.contributor.author | Angel Martinez-Gonzalez, Miguel | |
dc.contributor.author | Salas-Salvado, Jordi | |
dc.contributor.author | Corella, Dolores | |
dc.contributor.author | Gomez-Gracia, Enrique | |
dc.contributor.author | Fiol Sala, Miquel | |
dc.contributor.author | Manuel Santos, Jose | |
dc.contributor.author | Fito, Montserrat | |
dc.contributor.author | Aros, Fernando | |
dc.contributor.author | Serra-Majem, Lluis | |
dc.contributor.author | Pinto, Xavier | |
dc.contributor.author | Basora, Josep | |
dc.contributor.author | Vicente Sorli, Jose | |
dc.contributor.author | Munoz, Miguel-Angel | |
dc.contributor.author | PREDIMED Study Investigators | |
dc.date.accessioned | 2024-07-03T11:09:31Z | |
dc.date.available | 2024-07-03T11:09:31Z | |
dc.date.issued | 2014-08-26 | |
dc.identifier.citation | Mejia-Lancheros C, Estruch R, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Gomez-Gracia E, et al. Blood pressure values and depression in hypertensive individuals at high cardiovascular risk. BMC Cardiovasc Disord. 2014 Aug 26;14:109. | en |
dc.identifier.issn | 1471-2261 | |
dc.identifier.other | http://hdl.handle.net/20.500.13003/11159 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/20008 | |
dc.description.abstract | Background: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. Methods: Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic factors, body mass index, lifestyle, diabetes, dyslipidemia, and antihypertensive treatment), was performed. Results: Depressive patients, with and without antidepressant treatment, had better blood pressure control (OR: 1.28, CI 95%: 1.06-1.55, and OR: 1.30, CI 95%: 1.03-1.65, respectively) than non-depressive ones. Regarding blood pressure levels, systolic blood pressure values (mmHg) were found to be lower in both treated and untreated depressive patients (Log coefficient Beta: -1.59, 95% CI: -0.50 to -2.69 and Log coefficient Beta: -3.49, 95% CI: -2.10 to -4.87, respectively). Conclusions: Among hypertensive patients at high cardiovascular risk, the control of blood pressure was better in those diagnosed with depression. | en |
dc.description.sponsorship | This study was supported by the official funding agency for biomedical research of the Spanish government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, RTIC RD 06/0045) and through Centro de Investigacion Biomedica en Red de Fisiopatologia de la Obesidad y Nutricion [CIBERobn]), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigacion Sanitaria-Fondo Europeo de Desarrollo Regional (PI04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, and P11/02505), Ministerio de Ciencia e Innovacion (AGL-200913906-C02 and AGL2010-22319-C03), Fundacion Mapfre 2010, Consejeria de Salud de la Junta de Andalucia (PI0105/2007), Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (ACOMP06109, GVACOMP2010-181, GVACOMP2011-151, CS2010AP-111, CS2011-AP-042), and Regional Government of Navarra (P27/2011). None of the institutions described above have influenced the design, collection, analysis, and interpretation of data; the writing of the manuscript; and the decision to submit the manuscript for publication. | es_ES |
dc.language.iso | eng | en |
dc.publisher | BioMed Central (BMC) | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Hypertension | |
dc.subject | Depression | |
dc.subject | Blood pressure | |
dc.subject.mesh | Aged, 80 and over | * |
dc.subject.mesh | Aged | * |
dc.subject.mesh | Humans | * |
dc.subject.mesh | Depression | * |
dc.subject.mesh | Hypertension | * |
dc.subject.mesh | Middle Aged | * |
dc.subject.mesh | Blood Pressure | * |
dc.subject.mesh | Cross-Sectional Studies | * |
dc.subject.mesh | Male | * |
dc.subject.mesh | Multivariate Analysis | * |
dc.subject.mesh | Chi-Square Distribution | * |
dc.subject.mesh | Risk Factors | * |
dc.subject.mesh | Antidepressive Agents | * |
dc.subject.mesh | Treatment Outcome | * |
dc.subject.mesh | Odds Ratio | * |
dc.subject.mesh | Antihypertensive Agents | * |
dc.subject.mesh | Linear Models | * |
dc.subject.mesh | Logistic Models | * |
dc.title | Blood pressure values and depression in hypertensive individuals at high cardiovascular risk | en |
dc.type | research article | en |
dc.rights.license | Attribution 4.0 International | * |
dc.identifier.pubmedID | 25160563 | es_ES |
dc.format.volume | 14 | es_ES |
dc.format.page | 109 | es_ES |
dc.identifier.doi | 10.1186/1471-2261-14-109 | |
dc.relation.publisherversion | https://dx.doi.org/10.1186/1471-2261-14-109 | en |
dc.identifier.journal | BMC Cardiovascular Disorders | es_ES |
dc.rights.accessRights | open access | en |
dc.subject.decs | Modelos Lineales | * |
dc.subject.decs | Antihipertensivos | * |
dc.subject.decs | Resultado del Tratamiento | * |
dc.subject.decs | Antidepresivos | * |
dc.subject.decs | Modelos Logísticos | * |
dc.subject.decs | Oportunidad Relativa | * |
dc.subject.decs | Distribución de Chi-Cuadrado | * |
dc.subject.decs | Análisis Multivariante | * |
dc.subject.decs | Masculino | * |
dc.subject.decs | Hipertensión | * |
dc.subject.decs | Estudios Transversales | * |
dc.subject.decs | Factores de Riesgo | * |
dc.subject.decs | Presión Sanguínea | * |
dc.subject.decs | Humanos | * |
dc.subject.decs | Persona de Mediana Edad | * |
dc.subject.decs | Depresión | * |
dc.subject.decs | Anciano | * |
dc.subject.decs | Anciano de 80 o más Años | * |
dc.identifier.scopus | 2-s2.0-84906836736 | |
dc.identifier.wos | 341033100001 | |
dc.identifier.pui | L600015933 |
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