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dc.contributor.author | Montoya, Alonso | |
dc.contributor.author | Hervas, Amaia | |
dc.contributor.author | Fuentes, Joaquin | |
dc.contributor.author | Cardo-Jalon, Esther | |
dc.contributor.author | Polavieja, Pepa | |
dc.contributor.author | Quintero, Javier | |
dc.contributor.author | Tannock, Rosemary | |
dc.date.accessioned | 2024-07-03T11:01:13Z | |
dc.date.available | 2024-07-03T11:01:13Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Montoya A, Hervas A, Fuentes J, Cardo Jalon E, Polavieja P, Quintero J, et al. Cluster-randomized, controlled 12-month trial to evaluate the effect of a parental psychoeducation program on medication persistence in children with attention-deficit/hyperactivity disorder. Neuropsychiatr Dis Treat. 2014;10:1081-92. | en |
dc.identifier.other | http://hdl.handle.net/20.500.13003/17332 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/19948 | |
dc.description.abstract | Background: This multicenter, cluster-randomized, nonblinded study evaluated the effect of parental psychoeducation on medication persistence among children and adolescents with newly diagnosed attention-deficit/hyperactivity disorder (ADHD). Methods: Patients received standard medication alone or medication plus a parental psychoeducation program, and were followed for 12 months. The primary endpoint was time to withdrawal or termination of medication due to any cause. Secondary endpoints included change in ADHD symptom severity, functional outcome, program satisfaction, and safety. Results: A total of 208 patients completed the study, which was terminated early because recruitment had ceased. At 12 months, there was no significant difference between the psychoeducation and control groups in the proportion of patients who discontinued pharmacologic treatment (13.2% versus 14.3%, respectively; size effect -0.3, P=0.34; hazard ratio 0.72, 95% confidence interval 0.36-1.43). Psychoeducation was associated with a significantly greater improvement in ADHD symptoms but not in functional outcome. Parental satisfaction with psychoeducation was high, and satisfaction with pharmacologic treatment was significantly greater in the psychoeducation group. There were no safety concerns. Conclusion: No significant advantage for parental psychoeducation plus medication over medication alone in terms of time to medication withdrawal was observed. Psychoeducation had inconsistent but interesting effects on other outcomes. | en |
dc.description.sponsorship | AM and PP are full-time employees of and shareholders in Eli Lilly. AH is a consultant for Eli Lilly, and a consultant and speaker for Shire. In the past 3 years, JF has participated in advisory activities, unrestricted educational activities, and research projects sponsored by Janssen, Eli Lilly, Shire, Roche, and public/not for profit agencies. EC has received compensation for serving as a consultant or speaker. Her institution has received research support or royalties from Eli Lilly, the Health Spanish Ministry Research Fund, the Ministry of Education Grant Research, Shire, and UCB. JQ has served as an investigator for Janssen-Cilag and Shire, and as a speaker for Janssen-Cilag, Shire, and Eli Lilly. RT was a member of the DSM-5 Work Group on ADHD and externalizing disorders, and has received speaker fees for an unrestricted talk, consultancy, and an advisory board meeting from Eli Lilly and Shire in the past 3 years. The authors acknowledge the editorial support provided by David Peters and Sue Chambers of Rx Communications, Mold, UK, which was funded by Eli Lilly and Co. | es_ES |
dc.language.iso | eng | en |
dc.publisher | Dove Medical Press | en |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/ | * |
dc.subject | Psychoeducation | |
dc.subject | Medication persistence | |
dc.subject | Attention-deficit/hyperactivity disorder | |
dc.subject | Adjunctive psychoeducation | |
dc.subject | Parents | |
dc.title | Cluster-randomized, controlled 12-month trial to evaluate the effect of a parental psychoeducation program on medication persistence in children with attention-deficit/hyperactivity disorder | en |
dc.type | research article | en |
dc.rights.license | Attribution-NonCommercial 3.0 Unported | * |
dc.identifier.pubmedID | 24966679 | es_ES |
dc.format.volume | 10 | es_ES |
dc.format.page | 1081-1092 | es_ES |
dc.identifier.doi | 10.2147/NDT.S62487 | |
dc.identifier.e-issn | 1178-2021 | es_ES |
dc.relation.publisherversion | https://dx.doi.org/10.2147/NDT.S62487 | en |
dc.identifier.journal | Neuropsychiatric Disease and Treatment | es_ES |
dc.rights.accessRights | open access | en |
dc.identifier.scopus | 2-s2.0-84902573455 | |
dc.identifier.wos | 338423300005 | |
dc.identifier.pui | L373339437 |
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