Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/18569
Título
Association between common cardiovascular risk factors and clinical phenotype in patients with hypertrophic cardiomyopathy from the European Society of Cardiology (ESC) EurObservational Research Programme (EORP) Cardiomyopathy/Myocarditis registry.
Autor(es)
Lopes, Luis R | Losi, Maria-Angela | Sheikh, Nabeel | Laroche, Cécile | Charron, Philippe | Gimeno, Juan | Kaski, Juan P | Maggioni, Aldo P | Tavazzi, Luigi | Arbustini, Eloisa | Brito, Dulce | Celutkiene, Jelena | Hagege, Albert | Linhart, Ales | Mogensen, Jens | Garcia-Pinilla, José Manuel | Ripoll-Vera, Tomas | Seggewiss, Hubert | Villacorta, Eduardo | Caforio, Alida | Elliott, Perry M | Cardiomyopathy Registry Investigators Group
Fecha de publicación
2022
Idioma
Inglés
Tipo de documento
research article
Resumen
The interaction between common cardiovascular risk factors (CVRF) and hypertrophic cardiomyopathy (HCM) is poorly studied. We sought to explore the relation between CVRF and the clinical characteristics of patients with HCM enrolled in the EURObservational Research Programme (EORP) Cardiomyopathy registry. 1739 patients with HCM were studied. The relation between hypertension (HT), diabetes (DM), body mass index (BMI), and clinical traits was analysed. Analyses were stratified according to the presence or absence of a pathogenic variant in a sarcomere gene. The prevalence of HT, DM, and obesity (Ob) was 37, 10, and 21%, respectively. HT, DM, and Ob were associated with older age (P Common CVRF are associated with a more severe HCM phenotype, suggesting a proactive management of CVRF should be promoted. An interaction between genotype and CVRF was observed for some traits.
Palabras clave
Cardiovascular risk factors | Diabetes | Genotype | Hypertension | Hypertrophic cardiomyopathy | Obesity
MESH
Female | Humans | Cardiovascular Diseases | Risk Factors | Cardiomyopathy, Hypertrophic | Cardiomyopathies | Ventricular Dysfunction, Left | Hypertension | Obesity | Heart Disease Risk Factors
DOI
Aparece en las colecciones
- Investigación > IIS > IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
- Investigación > IIS > IBIMA-Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (Andalucía)
- Investigación > IIS > IBSAL - Instituto de Investigación Biómedica de Salamanca (Castilla y León)
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