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dc.contributor.author | Ruiz-López, María José | |
dc.contributor.author | Aguilera-Sepúlveda, Pilar | |
dc.contributor.author | Cebrián-Camisón, Sonia | |
dc.contributor.author | Figuerola, Jordi | |
dc.contributor.author | Magallanes, Sergio | |
dc.contributor.author | Varona Fernandez, Sarai | |
dc.contributor.author | Cuesta de la Plaza, Isabel | |
dc.contributor.author | Cano-Gómez, Cristina | |
dc.contributor.author | Sánchez-Mora, Patricia | |
dc.contributor.author | Camacho, Juan | |
dc.contributor.author | Sánchez-Peña, Carolina | |
dc.contributor.author | Marchena, Francisco José | |
dc.contributor.author | Ameyugo, Ulises | |
dc.contributor.author | Ruíz, Santiago | |
dc.contributor.author | Sánchez-Seco, María Paz | |
dc.contributor.author | Agüero, Montserrat | |
dc.contributor.author | Jiménez-Clavero, Miguel Ángel | |
dc.contributor.author | Fernández-Pinero, Jovita | |
dc.contributor.author | Vazquez, Ana | |
dc.date.accessioned | 2024-02-09T11:54:23Z | |
dc.date.available | 2024-02-09T11:54:23Z | |
dc.date.issued | 2023-12-01 | |
dc.identifier.citation | Viruses. 2023 Dec 1;15(12):2372. | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/17695 | |
dc.description.abstract | West Nile Virus (WNV) is a mosquito vector-borne zoonosis with an increasing incidence in Europe that has become a public health concern. In Spain, although local circulation has been known for decades, until 2020, when a large outbreak occurred, West Nile Virus cases were scarce and mostly occurred in southern Spain. Since then, there have been new cases every year and the pathogen has spread to new regions. Thus, monitoring of circulating variants and lineages plays a fundamental role in understanding WNV evolution, spread and dynamics. In this study, we sequenced WNV consensus genomes from mosquito pools captured in 2022 as part of a newly implemented surveillance program in southern Spain and compared it to other European, African and Spanish sequences. Characterization of WNV genomes in mosquitoes captured in 2022 reveals the co-circulation of two WNV lineage 1 variants, the one that caused the outbreak in 2020 and another variant that is closely related to variants reported in Spain in 2012, France in 2015, Italy in 2021-2022 and Senegal in 2012-2018. The geographic distribution of these variants indicates that WNV L1 dynamics in southern Europe include an alternating dominance of variants in some territories. | es_ES |
dc.description.sponsorship | This work was funded by Junta de Andalucía contract “63/22“, the Agencia Estatal de Investigación (project PID2020-118921RJ-100/AEI/10.13039/501100011033) and INIA-MAPA agreements EG17-141 and AEG21-198, INIA grant E-RTA2015-00002-C02-00 and the Instituto de Salud Carlos III Project PI19CIII/00014 and the European Commission-NextGenerationEU (Regulation EU 2020/2094), through CSIC’s Global Health Platform (PTI Salud Global+). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Culex | es_ES |
dc.subject | Flavivirus | es_ES |
dc.subject | Genetic variants | es_ES |
dc.subject | Spain | es_ES |
dc.subject | Vector-borne diseases | es_ES |
dc.subject | WNV lineage 1 | es_ES |
dc.subject | Zoonosis | es_ES |
dc.subject.mesh | West Nile virus | es_ES |
dc.subject.mesh | West Nile Fever | es_ES |
dc.subject.mesh | Culicidae | es_ES |
dc.subject.mesh | Animals | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Spain | es_ES |
dc.subject.mesh | Europe | es_ES |
dc.title | Re-Emergence of a West Nile Virus (WNV) Variant in South Spain with Rapid Spread Capacity | es_ES |
dc.type | research article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 38140614 | es_ES |
dc.format.volume | 15 | es_ES |
dc.format.number | 12 | es_ES |
dc.format.page | 2372 | es_ES |
dc.identifier.doi | 10.3390/v15122372 | es_ES |
dc.contributor.funder | Regional Government of Andalusia (España) | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación (España) | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (España) | es_ES |
dc.contributor.funder | Unión Europea. Comisión Europea. NextGenerationEU | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1999-4915 | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/v15122372 | es_ES |
dc.identifier.journal | Viruses | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Microbiología | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Microbiología::Unidades Comunes Científico-Técnicas (UCCT) | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/2020/2094 | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PID2020-118921RJ-100 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/EG17-141 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/AEG21-198 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/E-RTA2015-00002-C02-00 | es_ES |
dc.relation.projectFIS | info:fis/Instituto de Salud Carlos III/Programa Estatal de Generación de Conocimiento y Fortalecimiento del Sistema Español de I+D+I/Subprograma Estatal de Generación de Conocimiento/PI19-ISCIII Modalidad Proyectos de Investigacion en Salud Intramurales. (2019)/PI19CIII/00014 | es_ES |