Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/17343
Título
Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy.
Autor(es)
Fecha de publicación
2017-10-28
Idioma
Inglés
Tipo de documento
research article
Resumen
Dry eye syndrome is a complex and insidious pathology with a high level of prevalence among the human population and with a consequently high impact on quality of life and economic cost. Currently, its treatment is symptomatic, mainly based on the control of lubrication and inflammation, with significant limitations. Therefore, the latest research is focused on the development of new biological strategies, with the aim of regenerating affected tissues, or at least restricting the progression of the disease, reducing scar tissue, and maintaining corneal transparency. Therapies range from growth factors and cytokines to the use of different cell sources, in particular mesenchymal stem cells, due to their multipotentiality, trophic, and immunomodulatory properties. We will review the state of the art and the latest advances and results of these promising treatments in this pathology.
Palabras clave
allogenic cell therapy | dry eye | growth factor | keratoconjunctivitis sicca | lacrimal gland | mesenchymal stem cell | regenerative medicine
MESH
Animals | Cell- and Tissue-Based Therapy | Dry Eye Syndromes | Humans | Intercellular Signaling Peptides and Proteins | Regenerative Medicine | Stem Cell Transplantation | Stem Cells
DOI
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