Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/16776
Título
Genomic characterisation of respiratory syncytial virus: a novel system for whole genome sequencing and full-length G and F gene sequences
Autor(es)
Iglesias-Caballero, Maria ISCIII | Camarero-Serrano, Sara ISCIII | Varona Fernandez, Sarai ISCIII | Mas-Lloret, Vicente ISCIII | Calvo, Cristina | García, María Luz | García-Costa, Juan | Vazquez-Moron, Sonia ISCIII | Monzon-Fernandez, Sara ISCIII | Campoy, Albert ISCIII | Cuesta de la Plaza, Isabel ISCIII | Pozo Sanchez, Francisco ISCIII | Casas Flecha, Inmaculada ISCIII
Fecha de publicación
2023-12
Cita
Euro Surveill. 2023 Dec;28(49).
Idioma
Inglés
Tipo de documento
research article
Resumen
To advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for challenging cases with low viral load. These methods monitor RSV genetic diversity to inform molecular epidemiology, vaccine effectiveness and treatment strategies, contributing also to the standardisation of surveillance in a new era of vaccines.
Versión en línea
DOI
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