Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/14929
Título
Illness Severity in Hospitalized Influenza Patients by Virus Type and Subtype, Spain, 2010-2017
Autor(es)
Delgado-Sanz, Concepcion ISCIII | Mazagatos, Clara ISCIII | Oliva Dominguez, Jesus Angel ISCIII | Gherasim, Alin Manuel ISCIII | Larrauri, Amparo ISCIII
Fecha de publicación
2020-02
Cita
Emerg Infect Dis. 2020 Feb;26(2):220-228.
Idioma
Inglés
Tipo de documento
journal article
Resumen
We conducted a retrospective cohort study to assess the effect of influenza virus type and subtype on disease severity among hospitalized influenza patients in Spain. We analyzed the cases of 8,985 laboratory-confirmed case-patients hospitalized for severe influenza by using data from a national surveillance system for the period 2010-2017. Hospitalized patients with influenza A(H1N1)pdm09 virus were significantly younger, more frequently had class III obesity, and had a higher risk for pneumonia or acute respiratory distress syndrome than patients infected with influenza A(H3N2) or B (p<0.05). Hospitalized patients with influenza A(H1N1)pdm09 also had a higher risk for intensive care unit admission, death, or both than patients with influenza A(H3N2) or B, independent of other factors. Determining the patterns of influenza-associated severity and how they might differ by virus type and subtype can help guide planning and implementation of adequate control and preventive measures during influenza epidemics.
Palabras clave
Spain | Influenza A(H1N1)pdm09 | Influenza A(H3N2) | Influenza B | Influenza hospitalizations | Respiratory infections | Severe influenza | Surveillance | Viral subtypes | Viral types | Viruses | Influenza
MESH
Hospitalization | Adolescent | Adult | Age Factors | Aged | Aged, 80 and over | Child | Child, Preschool | Cohort Studies | Female | Humans | Infant | Infant, Newborn | Influenza A Virus, H1N1 Subtype | Influenza A Virus, H3N2 Subtype | Influenza, Human | Male | Middle Aged | Retrospective Studies | Risk Factors | Severity of Illness Index | Spain | Young Adult
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