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dc.contributor.authorMartinez-Martin, Pablo 
dc.contributor.authorManuel Rojo-Abuin, Jose
dc.contributor.authorRizos, Alexandra
dc.contributor.authorRodriguez-Blazquez, Carmen 
dc.contributor.authorTrenkwalder, Claudia
dc.contributor.authorPerkins, Lauren
dc.contributor.authorSauerbier, Anna
dc.contributor.authorOdin, Per
dc.contributor.authorAntonini, Angelo
dc.contributor.authorChaudhuri, Kallol Ray
dc.contributor.authorInternational Parkinson's Disease Non-Motor Group (PDNMG)
dc.contributor.authorEUROPAR Study Group
dc.contributor.authorKing's Parkinson's Disease Pain Scale (KPPS)
dc.identifier.citationNPJ Parkinsons Dis. 2017 Mar 15;3:8.es_ES
dc.description.abstractIn Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients experienced more pain modalities than controls. In patients, Pain around joints (King's Parkinson's disease pain scale item 1) and Pain while turning in bed (item 8) were the most prevalent types of pain, whereas Burning mouth syndrome (item 11) and Pain due to grinding teeth (item 10) showed the lowest frequency. The total number of experienced pain modalities closely correlated with the PDQ-8 index, but not with other variables. For all pain types except Pain around joints (item 1) and pain related to Periodic leg movements/RLS (item 7), patients with pain had significantly worse health-related quality of life. The influence of pain, as a whole, on the health-related quality of life was not remarkable after adjustment by other variables. When the particular types of pain were considered, adjusted by sex, age, and Parkinson's disease duration, pain determinants were different for EQ-5D-3L and PDQ-8. King's Parkinson's disease pain scale allows exploring the distribution of the diverse syndromic pain occurring in Parkinson's disease and its association with health-related quality of life.es_ES
dc.description.sponsorshipThe study was funded by a Parkinson’s UK innovation grant, and adopted to the UK National Institute for Health Research (NIHR) national portfolio of studies and supported by NIHR Mental Health Biomedical Research Center and Dementia Unit at South London and Maudsley NHS Foundation Trust and King’s College London.es_ES
dc.publisherNature Publishing Group es_ES
dc.relation.isversionofPublisher's versiones_ES
dc.titleDistribution and impact on quality of life of the pain modalities assessed by the King's Parkinson's disease pain scalees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderParkinson's UKes_ES
dc.contributor.funderNational Institute for Health Research (Reino Unido)es_ES
dc.contributor.funderNIHR - Mental Health Biomedical Research Centre (Reino Unido)es_ES
dc.contributor.funderSouth London and Maudsley NHS Foundation Trust (Reino Unido)es_ES
dc.contributor.funderImperial College London (Reino Unido)es_ES
dc.identifier.journalNPJ Parkinson's Diseasees_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES

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Atribución 4.0 Internacional
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